摘要
目的探究影响基底动脉闭塞(BAO)患者病情严重程度及进展的危险因素,为疾病发展的预测和治疗的选择提供帮助。方法回顾性收集确诊为BAO的127例患者的临床资料,分别将患者分为严重卒中组及轻、中度卒中组,病情进展组及未进展组,经单因素分析及多因素logistic回归分析得出危险因素。结果在严重卒中组男性、吸烟史和入院时体温升高率高于轻、中度卒中组(P<0.05),而脑梗死病史少于轻、中度卒中组(P<0.05)。吸烟史和入院时体温升高为影响患者入院时病情严重程度的独立危险因素,OR值分别为0.405和0.070,95%可信区间为(0.182,0.902)和(0.020,0.242)。发病前有前驱症状为影响患者入院后病情进展的显著保护因素,OR=0.435,95%可信区间为(0.212,0.894)。结论本文探究了对BAO病情严重程度和病情进展的影响因素,并得出相应的危险因素和保护因素,可能会在BAO病情的预测及治疗方面起到一定指导作用。
Objective To investigate the risk factors affecting severity and progression of patients with basilar artery occlusion（ BAO） in order to provide help for the development prediction and treatment of the disease. Methods Clinical data of 127 patients confirmed as having BAO was retrospectively analyzed,and the patients were divided into severe stroke group（ n = 58） and mild-moderate stroke group（ n = 69）. Patients were also divided into aggravation group（ n = 73） and non aggravation group（ n = 54）. The risk factors were analyzed using single factor and multiple factors logistic regression analysis methods. Results In severe stroke group,the numbers of male,smoking history and fervescence rate upon admission were higher（ P〈0. 05）,while number of patients with cerebral infarction history was lower than those in mild-moderate stroke group（ P〈0. 05）. The smoking history and fervescence upon admission were the independent risk factors affecting severity of patient＇s conditions upon admission,and the odd ratio（ OR） value of severity were 0. 405 and 0. 070 respectively,and corresponding 95% confidence intervals were（ 0. 182,0. 902） and（ 0. 020,0. 242） respectively. Incidence of prodromal symptom before the pathogenesy was the significant protection factor affecting severity of patient ＇s conditions after admission,and the OR value was 0. 435,and 95% confidence interval was（ 0. 212,0. 894）. Conclusion The factors affecting severity and progression of BAO patients are analyzed in this study,and related risk and protection factors are identified,which may be helpful for prediction and treatment of BAO patients.
出处
《解放军医药杂志》
CAS
2016年第3期33-36,共4页
Medical & Pharmaceutical Journal of Chinese People’s Liberation Army
基金
辽宁省科技攻关计划(2013225089
2014225008)
关键词
基底动脉闭塞
回归分析
危险因素
Basilar artery occlusion
Regression analysis
Risk factors
