摘要
目的探讨艾司西酞普兰与帕罗西汀治疗老年抑郁症的临床疗效。方法选择老年抑郁症患者60例的临床资料进行回顾性分析,A组采用艾司西酞普兰治疗,B组采用帕罗西汀治疗,每组各30例。比较两组治疗前后的临床疗效及不良反应。结果两组治疗后HAMD评分下降(P<0.01)。治疗后1周A组评分低于B组,差异有统计学意义(P<0.05)。治疗后4周、6周两组比较差异无统计学意义(P>0.05)。两组治疗后不同时间点TESS评分无差异(P>0.05);两组间治疗后不同时间点TESS评分比较差异无统计学意义(P>0.05)。结论艾司西酞普兰治疗老年抑郁症起效更快,并且不良反应少。
Objective To discuss clinical efficacy of escitalopram and paroxetine in the treatment of senile depression. Methods Clinical data of 60 cases with senile depression were respectively analyzed. Group A was treated with escitalopram,and group B was treated with paroxetine,each group of 30 cases,clinical efficacy and adverse reactions of two groups were compared. Results After treatment,HAMD of two groups were lower than that before treatment（P〈0.01）. HAMD of group A after 1 weeks of treatment was lower than group B,which showed significant difference（P〈0.05）. After 4,6 weeks of treatment,HAMD of two groups showed no significant difference（P〉0.05）. TESS of two groups in different time after treatment showed no significant difference（P〉0.05）. TESS between two groups in different time after treatment showed no significant difference（P〉0.05）. Conclusion Escitalopram in the treatment of senile depression takes effect faster,and with less adverse reactions.
出处
《中国卫生标准管理》
2016年第3期86-88,共3页
China Health Standard Management
