摘要
目的探讨降钙素原(PCT)联合红细胞分布宽度对胰腺炎病情严重程度的评估价值。方法选取2013年12月至2015年12月收治的98例胰腺炎患者,其中包括重度胰腺炎(SAP)患者49例,轻度胰腺炎(MAP)患者49例,对比两组患者PCT、红细胞分布宽度、C反应蛋白水平及APACHEⅡ评分的差异情况;记录SAP组患者生存情况,根据预后情况分为存活组(38例)和死亡组(11例),逆向分析两组患者PCT、红细胞分布宽度(RDW)、C反应蛋白(CRP)的水平及APACHEⅡ评分的差异,SAP组RDW和PCT分别与重症评分的相关性。结果 SAP组患者PCT(3.31±1.08)μg/L,RDW(17.52±4.91)%,CRP(134.58±28.94)mg/L水平及APACHEⅡ评分(18.22±7.31)分明显高于MAP组的(0.40±0.12)μg/L,(14.17±2.31)%,(12.33±3.61)mg/L,(7.82±1.04)分,差异具有统计学意义(P<0.05);死亡组患者PCT(4.21±1.54)μg/L,RDW(18.43±3.95)%,CRP(149.21±29.63)mg/L水平及APACHEⅡ评分(19.52±9.31)分明显高于存活组的(2.05±0.22)μg/L,(15.69±1.94)%,(53.44±19.62)mg/L,(13.11±4.15)分,差异具有统计学意义(P<0.05)。RDW水平与Ranson评分、APACHEⅡ评分均呈正相关(r=0.389和0.412,P均<0.01);血清PCT水平与Ranson评分、APACHEⅡ评分均呈正相关(r=0.443和0.514,P均<0.01)。结论 PCT联合红细胞分布宽度可以作为评价胰腺炎患者病情严重程度的指标,且对判断患者的预后有着重要的临床价值。
Objective To explore the value of PCT combined with red blood cell distribution width in assessing the severity of pancreatitis. Methods 98 cases of pancreatitis patients including 49 cases of severe pancreatitis（ SAP） patients and 49 cases of patients with mild acute pancreatitis（ map） from December 2013 to December 2015 were selected. PCT,red cell distribution width,C- reactive protein level and APACHE II score differences of two groups of patients were compared. We recorded the patients survival of SAP group. According to the prognosis,these patients were divided into survival group（ 38 cases） and death group（ 11 cases）. We analyzed the procalcitonin（ PCT）,red cell distribution width（ RDW）,C- reactive protein（ CRP） level and APACHE II score differences,and RDW and PCT of SAP group in correlation with severe score. Results The patients of SAP group with PCT（ 3. 31 ± 1. 08） μg / L and RDW（ 17. 52 ± 4. 91） %,CRP（ 134. 58 ± 28. 94） mg / L level and APACHE II score（ 18. 22 ± 7. 31） was significantly higher than those of map group with PCT（ 0. 40 ± 0. 12） μg / L,（ 14. 17 ± 2.31） %,（ 12. 33 ± 3. 61） mg / L and APACHE II score（ 7. 82 ± 1. 04）,with statistically significant difference（ P〈0. 05）. The patients of death group with PCT（ 4. 21 ± 1. 54） μg / L,RDW（ 18. 43 ± 3. 95） %,CRP（ 149. 21 ± 29. 63） mg / L and APACHE II score（ 19. 52 ± 9. 31）was significantly higher than those of survival group with PCT（ 2. 05 ± 0. 22） μg / L,（ 15. 69 ± 1. 94） % and（ 53. 44 ± 19. 62） mg / L and APACHE II score（ 13. 11 ± 4. 15）,with statistically significant difference（ P〈0. 05）. RDW level and Ranson score,APACHEⅡ scores were positively correlated（ r = 0. 389,respectively,and 0. 412,P〈0. 01）. Serum PCT levels and Ranson score,APACHEⅡ score showed a positive correlation（ r = 0. 443,respectively,and 0. 514,P〈0. 01）. Conclusion PCT combined with the red blood cell distribution width can be used as an i
出处
《临床和实验医学杂志》
2016年第6期554-557,共4页
Journal of Clinical and Experimental Medicine
