摘要
目的探讨中西医结合疗法对临床急性脑梗死(ACI)患者的疗效及对血管性血友病因子(vWF)、血清脂联素(APN)水平的影响。方法选取2013年6月至2014年6月本院收治的ACI患者96例,依据随机数字表法分为研究组与对照组各48例。对照组予以西医常规治疗,研究组另给予中药汤剂治疗,比较治疗2周后两组的疗效,治疗前后的血vWF、APN水平及神经功能缺损(NIHSS)评分,分析NIHSS评分与血vWF、APN水平的相关性。结果研究组的总有效率93.75%(45/48)明显高于对照组77.08%(37/48),差异有统计学意义(P<0.05)。治疗后研究组的血vWF水平明显低于对照组,APN水平明显高于对照组,差异均有统计学意义(P<0.05)。两组治疗后NIHSS评分均有改善,但研究组明显低于对照组,差异有统计学意义(P<0.05)。依照Pearson相关分析可知,NIHSS评分与血vWF呈正相关,与APN呈负相关。结论中西医结合治法对ACI患者具有较好的疗效,还可有效改善患者的血vWF、APN指标水平,值得临床推广。
Objective To study the efficacy of integrated traditional Chinese and Western medicine in the treatment of acute cerebral infarction（ACI）and its influence on blood vWF and APN levels.Methods Totally 96 cases of ACI in our hospital from June 2013 to June 2014 were selected and randomly divided into the study group and control group according to the digits table method,48 cases in each group.The control group was given the conventional treatment of Western medicine,while the study group was given the Chinese medicine decoction on the basis of the control group.The curative effects after 2-week treatment were compared between the two groups,the blood vWF and APN levels and the neural function defect（NIHSS）score in the two groups were compared between before and after treatment.The correlation between the NIHSS score with blood vWF and APN levels was analyzed.ResultsThe total effective rate in the study group was 93.75%（45/48）,which was significantly higher than in the control group 77.08%（37/48）,the difference was statistically significant（P〈0.05）.The blood vWF level after treatment in the study group was significantly lower than that in the control group,while the APN level was significantly higher than that in the control group,the differences were statistically significant（P〈0.05）.The NIHSS scores after treatment in the two groups were improved,but the study group was significantly lower than the control group,the difference was statistically significant（P〈0.05）.According to the Pearson correlation analysis,the NIHSS scores were positively correlated with blood vWF and negatively correlated with APN.Conclusion The treatment of integrated traditional Chinese and Western medicine has good curative effect in ACI patients,can effectively improve the blood vWF and APN levels and is worthy of clinical popularization.
出处
《检验医学与临床》
CAS
2016年第6期768-769,772,共3页
Laboratory Medicine and Clinic
关键词
中西医结合
急性脑梗死
血管性血友病因子
血清脂联素
integrated traditional Chinese and Western medicine
acute cerebral infarction
vWF
APN
