摘要
目的观察研究低分子肝素联合心理干预预防下肢骨折术后深静脉血栓的临床疗效。方法选取70例下肢骨折术的患者,随机分为观察组和对照组各35例,对照组给予下肢物理加压预防下肢骨折术后深静脉血栓,观察组给予低分子肝素联合心理干预预防下肢骨折术后深静脉血栓,比较2组患者血小板、凝血酶原时间（prothrombin time,PT）及活化部分凝血活酶时间（activated partial thromboplastin time,APTT）。结果观察组患者治疗后血小板为（188.59±36.93）×10~9/L,优于对照组（261.20±39.48）×10~9/L（P〈0.05）。观察组治疗后PT及APTT值分别为（16.16±2.21、36.89±4.39）s,优于对照组（13.26±2.10、31.16±4.13）s,（P〈0.05）。结论低分子肝素联合心理干预预防下肢骨折术后深静脉血栓的临床治疗效果确切。
Objective To observe clinical efficacy of low molecular weight heparin combined with psychological intervention in prevention of deep vein thrombosis after lower limb fracture. Methods 70 patients were randomly divided into observation group and control group（ n = 35）,in the control group were given physical pressure to prevent deep vein thrombosis after lower limb fracture,observation group was given low molecular weight heparin combined with psychological intervention, two groups of platelet, prothrombin time and activated partial thromboplastin time were compared.Results After treatment,in the observation group,the blood platelet was（ 188. 59 ± 36. 93） × 10~9/ L,better than the control group（ 261. 20 ± 39. 48）× 10~9/ L（ P〈0. 05）. PT and APTT values in the observation group after treatment were（ 16. 16 ± 2. 21,36. 89 ± 4. 39） s,better than the control group（ 13. 26 ± 2. 10,31. 16 ± 4. 13） s（ P〈0. 05）. Conclusion Low molecular weight heparin combined with psychological intervention in prevention of deep vein thrombosis after lower limb fracture has good clinical effect.
出处
《中国生化药物杂志》
CAS
2016年第1期104-105,108,共3页
Chinese Journal of Biochemical Pharmaceutics
关键词
低分子肝素
心理干预
下肢骨折术
深静脉血栓
low molecular weight heparin
psychological intervention
lower limb fracture surgery
deep vein thrombosis
