摘要
目的:观察口腔溃疡含漱液治疗急性白血病合并口腔溃疡的临床疗效。方法:将急性白血病患者化疗期间及化疗后合并口腔溃疡的88例患者随机分为对照组和观察组。对照组应用锡类散局部喷洒,观察组给予口腔溃疡含漱液,方药组成:生黄芪40 g,水牛角30 g,无花果20 g,牡丹皮12 g,生地榆12 g,生地黄12 g,生牡蛎20 g,水煎取汁,漱口。比较两组治疗后口腔溃疡程度、临床疗效及显效时间。结果:观察组发生口腔溃疡0度、Ⅰ度例数明显多于对照组(P<0.05);观察组有效率为94.1%,对照组有效率为48.6%,两组比较,差异有统计学意义(P<0.01);观察组治疗显效时间明显少于对照组(P<0.01)。结论:口腔溃疡含漱液治疗急性白血病合并口腔溃疡疗效显著。
Objective: To observe the clinical efficacy of TCM ulcer gargle in treatment of acute leukemia with oral ulcers. Methods:85 acute leukemia patients with oral ulcers during or after chemotherapy were randomly divided into control group and observation group. Xi Lei Powder was given to the control group in treatment,while TCM ulcer gargle were given to the observation group,which consists of: Raw Astragalus 40 g,Buffalo horn 30 g,Figs 20 g,Peony root 12 g,Raw Burnet 12 g,Raw Rehmannia 12 g,and Raw oysters 20 g. Compare the efficacy and effective time of the two groups after the treatment. Results: The number of oral ulcers cases in 0 degrees andⅠ degree was larger than that of the control group( P 〈 0. 05),with 94. 1% in observation group and48. 6% in the control group. The difference was statistically significant( P 〈 0. 01). The effective time of the observation group was significantly sooner than that of the control group( P 〈 0. 01). Conclusion: TCM ulcer gargle can achieve significant clinical effect in treatment of acute leukemia with oral ulcers.
出处
《中医学报》
CAS
2016年第3期322-324,共3页
Acta Chinese Medicine