摘要
桔梗和牛膝是两味常用的引经药。临床上常将桔梗比作"舟辑之剂",起到载药上行、开宣肺气之功效;用牛膝以达到引药下行、引血下行、引火下行的功效。通过对桔梗和牛膝两种药物的归经、升降浮沉、四气五味、现代药理的研究,探讨其引经机制,发现桔梗皂苷的表面活性所决定的增溶作用和对细胞膜通透性的影响,是桔梗引经作用的内在基础,牛膝引经之药理机制尚未有明确定论,从而进一步指导临床用药。
Jiegeng（ Radix Platycodonis） and Niuxi（ Radix Achyranthis Bidentatae） are two commonly-used guiding herbs. Clinically,Jiegeng（ Radix Platycodonis） is often compared to oar of the boat,with the effects of guiding drugs upward and promoting the dispersing function of the lung qi. Niuxi（ Radix Achyranthis Bidentatae） can guide the drugs,blood and fire downward. By the study on the meridian tropism,direction（ lifting,lowering,floating and sinking）,four properties and five tastes and the pharmocology of these two herbs,the mechanism of the guide was explored. It was discovered that the solubilization determined by the surface activity of the platycodin as well as the its influence on the cytomembrane permeability are the internal bases for the guiding action of Jiegeng（ Radix Platycodonis）. There was no clear conclusion for the pharmocological mechanism of the guiding action of Niuxi（ Radix Achyranthis Bidentatae）. This will further guide the clinical medication.
出处
《河南中医》
2016年第1期165-166,共2页
Henan Traditional Chinese Medicine
基金
江苏省中医管理局资助项目(编号:LZ09014)
关键词
引经药
桔梗
牛膝
guiding herbs
Jiegeng（Radix Platycodonis）
Niuxi（Radix Achyranthis Bidentatae）
