摘要
目的研究能量和蛋白质供给对老年患者肠外营养（parenteral nutrition,PN）支持时间的影响。方法回顾性研究上海交通大学医学院附属仁济医院临床营养科接受PN的老年住院患者。采集患者一般情况和PN相关指标。PN时间定义为PN开始至完全过渡至肠内营养的时间。目标供给量依据Schofield公式计算。PN提供的日能量供给占目标供给量〈75%为低能量组;75%～120%为正常能量组,〉120%为高能量组。结果共入选老年患者327例（男214例,女112例）,平均年龄（74.7±6.2）岁,接受PN的中位时间为12.2 d（3～96d）。多因素线性回归分析显示接受PN时BMI（B=-1.733,t=-2.899,P=0.004）和日能量供给（B=-6.437,t=-4.444,P〈0.001）是老年患者PN支持时间的重要预测因素。低能量组患者PN时间较正常能量组患者组明显延长（17.3 d比7.2 d,Z=-8.279,P〈0.001）;重度营养不良患者PN时间也较营养状况正常的患者显著延长（10.5 d比8.0 d,Z=-2.254,P=0.024）。结论 PN提供能量较低和营养状况差可延长老年患者PN支持时间。
Objective To evaluate the effects of calorie and protein supplementation on duration of parenteral nutrition（PN） in elderly patients. Methods A retrospective study was performed in elderly hospitalized patients who received PN prescribed by Department of Clinical Nutrition, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University. Descriptive and PN related data was obtained. Duration of PN was defined as the time from the start to the end of PN. Daily calorie goal was calculated by Sehofield equation. Low calorie group was defined as the ratio of daily calorie supplementation by PN to daily calorie goal was 〈75% ; the ratio ranged from 75% to 120% as normal calorie group and the ratio〉120% as high calorie group. Results 327 patients （214 male and 112 female, average age 74.7± 6. 2） were recuited for the study. The median duration of PN was 12. 2 d （3 ～ 96 d）. A multiple factors linear regression showed BMI scores （B=-1.733,t=-2. 899,P=0. 004） at the begin of PN and daily calorie supplementation by PN （B=-6.437,t= -4.444,P〈0. 001） were two predictive factors for duration of PN in elderly hospitalized patients. Duration of PN was obviously longer in low calorie group than that in normal calorie group （ 17. 3 d vs 7.2 d, Z=-8. 279, P〈0. 001 ）, while it was the same in patients with severe malnutrition compared with that in patients with normal nutrition （ 10. 5 d vs 8. 0 d ,Z= -2. 254,P= 0. 024）. Conclusions A low daily calorie supplementation by PN and a severe malnutrition status lengthen duration of PN.
出处
《实用老年医学》
CAS
2016年第3期203-205,208,共4页
Practical Geriatrics
关键词
能量供给
蛋白质供给
老年人
肠外营养
calorie supplementation
protein supplementation
aged
parenteral nutrition
