摘要
目的探讨磁共振弥散扩散张量成像(DTI)对急性一氧化碳中毒迟发性脑病(DEACMP)的临床应用价值。方法选取2012年12月至2015年2月我院确住院治疗的DEACMP患者30例,采用高压氧联合甲强龙治疗,治疗前后分别行MMSE智能量表、ADL生活能力量表评定和DTI扫描。结果治疗前后患者MMSE、Barthel评分、DTI参数ADC和FA值均有显著改善(P<0.05)。治疗前患者的MMSE评分与治疗前ADC值显著相关(r=0.38,P<0.05),治疗后MMSE评分也与治疗前ADC值显著相关(r=0.40,P<0.05)。结论DTI成像对DEACMP的病情进展、预后评估及临床治疗均具有重要意义。
Objective To investigate the value of DTI in the diagnosis of delayed encephalopathy after acute carbon monoxide poisoning（DEACMP）. Methods 30 DEACMP inpatients were received by our department of neurology from December 2012 to February 2015. MMSE, ADL function evaluation and DTI imaging were performed to patients in the period before and after treatment with hyperbaric oxygenation combined of methylprednisolone. Results The MMSE and ADL, ADC and FA values of DTI imaging were obviously improved after received treatment（P〈0.05）. MMSE scores before treatment were significantly associated with ADC values（r=0.38, P〈0.01）. MMSE scores were also significantly associated with ADC values after received treatment（r=0.40, P〈0.05）. Conclusions DTI imaging have important significance in condition judgment, prognosis and clinical of DEACMP.
出处
《中国医药指南》
2016年第7期20-21,共2页
Guide of China Medicine
