摘要
棕色脂肪和米色脂肪合称为产热脂肪,其生理作用为产热和消耗能量,激活产热脂肪是治疗肥胖和代谢性疾病的一条新途径,但无论是从来源、分化过程、生化特征、转录调控因素以及产热作用上,米色脂肪均有别于传统意义上的棕色脂肪。体育锻炼与脂肪细胞和产热过程密切相关,研究发现其可通过多种信号途径及方式影响棕色脂肪和米色脂肪的诱导分化和产热过程,且不同的运动方式对产热脂肪的代谢影响也存在争议。本文就棕色脂肪和米色脂肪近年来在体育锻炼方面的研究进展和争论作一综述。
Brown fat and beige fat are the so called thermogenic fat, thermogenisis and energy consumption are their physiological effect, activation of thermogenic fat is a new approach to the treatment of obesity and metabolic diseases, but they are different from the source, differentiation, biochemical characteristics, regulation of transcription factors and thermal effect. Physical exercise is associated with adipocyte and the thermogenisis process, researches indicated that it can affect differentiation and thermogenisis process via a variety of signal pathways and effects on brown fat and beige fat, and there has been debated on different modes of exercise affecting the differentiation and metabolism in thermogenic fat. This article reviews the advance and debate of brown fat and beige fat in physical exercise.
出处
《南京医科大学学报（自然科学版）》
CAS
CSCD
北大核心
2016年第1期12-18,共7页
Journal of Nanjing Medical University(Natural Sciences)
基金
中华医学会临床医学专项资金(13020120397
13040630448)
第三军医大学青年人才基金项目(SWH2013QN02)
