摘要
目的通过对血糖控制较理想的1型糖尿病合并妊娠患者进行动态血糖监测系统（CGMS）和自我血糖监测（sMBG），分析血糖的数据，探讨CGMS是否更有利于血糖的控制。方法选取2012年6月至2015年7月住院治疗的1型糖尿病合并妊娠患者25例，进行72h的CGMS监测，同时进行SMBG，记录餐前血糖、餐后2h血糖（2hBG）及凌晨2：00血糖。结果CGMS最高血糖值[（10．60±2．11）mmol／L]高于SMBG[（7．50±1．18）mmol／L]（P〈0．01）；CGMS最低血糖值[（3．60±1．06）mmol／L]低于SMBG[（4．50±1．15）mmol／L]（P〈0．01）；CGMS平均血糖值[（7．20±1.18）mmol／L]与SMBG[（7．30±1．15）mmol／L]比较差异无统计学意义（P〉0．05）。CGMS测出低血糖（血糖〈3．3mmol／L）占4．6％，SMBG测出低血糖占1．9％。通过CGMS提供的血糖谱信息指导患者的用药、饮食和运动，其49～72h时间段的餐前30rain血糖、2hBG、睡前血糖、凌晨2：00血糖较0～24h时间段明显下降（P〈0．05）。结论CGMS和SMBG两种血糖监测方法均能反映患者血糖的水平。CGMS较SMBG方法可以更好显示全天血糖动态变化情况，较好地评估血糖的漂移，以便更好地发现餐后高血糖及夜间低血糖。
Objective To explore the efficiency of continuous glucose monitoring system（CGMS） and blood glucose self-monitoring （SMBG）in evaluating blood glucose excursion in type 1 diabetes mellitus （T1DM） complicated with pregnancy. Methods Twenty-five patients having suffered from T1DM complicated with pregnancy were selected randomly during June 2012 to July 2015. All subjects underwent blood glucose monitoring by CGMS and SMBG for 72 h, including the data of blood glucose before meal, 2 h post-meal blood glucose （2hBG） and blood glucose at 2：00 AM. Results The level of the highest blood glucose in CGMS was significantly higher than that in SMBG： （10.60 ± 2.11） mmol/L vs. （7.50 ±1.18） mmol/L, P 〈 0.01. The level of the lowest blood glucose in CGMS was significantly lower than that in SMBG： （3.60 ± 1.06） mmol/L vs. （4.50 ± 1.15） mmol/L, P 〈 0.01. The level of mean blood glucose in CGMS and SMBG had no significant difference： （7.20 ± 1.18） mmol/L vs. （7.30 ± 1.15） mmol/L, P 〉 0.05. The rate of hypoglycemia（blood glucose 〈 3.3 mmol/L） in CGMS was 4.6%, and in SMBG was 1.9%. Through adjusting the treatment by CGMS, the blood glucose before meal, 2hBG and blood glucose at 2 ： 00 AM at 49 - 72 h were significantly lower thai＇/that at 0 - 24 h （P 〈 0.05）. Conclusions Compared with SMBG, CGMS has a relatively larger blood glucose monitoring range and can sensitively evaluate blood glucose excursion, CGMS provides a scientific basis to develop a more rational andeffective strategies for controlling diabetes.
出处
《中国医师进修杂志》
2016年第3期242-245,共4页
Chinese Journal of Postgraduates of Medicine
关键词
糖尿病
1型
妊娠
动态血糖监测系统
自我血糖监测
Diabetes mellitus, type 1
Pregnancy
Continuous glucose monitoring system
Blood glucose self-monitoring
