摘要
目的分析老年大疱性类天疱疮(BP)患者的临床特点及治疗方法。方法收集我院近13年来收治的老年(≥60岁)大疱性类天疱疮患者的临床资料并进行回顾性分析。结果共收集34例患者,平均年龄(73.6±8.1)岁;男女性别比为1.6∶1。轻、中、重度三组患者之间的年龄、病程、住院天数及合并基础病无统计学差异(P>0.05),而重度患者并发症发生率及激素用量明显高于其他两组(P<0.05)。所有患者经治疗后均好转出院。结论老年BP患者基础病非常常见,重度患者容易出现并发症。中重度患者常使用大剂量糖皮质激素治疗,轻度及部分中度患者使用米诺环素等三联疗法治疗有效。
Objective To analyze the clinical features and treatment of elderly patients with bullous pemphigoid. Methods The clinical data of elderly patients（aged 60 or above） with bullous pemphigoid in our hospital in recent 13 years were conducted and retrospectively analyzed. Results Thirty-four patients were collected. Mean age was（73.6 ± 8.1） years old. Sex ratio of male and female cases was 1.6 ： 1. No difference was found in age, course of disease, length of hospital stay and underlying disease between mild, moderate and severe cases（P〉0.05）. However, compared with the other two groups, the severe group had significantly higher incidence rate of complications and dosage of glucocorticoids（P〈0.05）. All patients were discharged after treatment. Conclusions It＇s very common to identify underlying disease in elderly bullous pemphigoid and complications in severe cases. We often use high-dose glucocorticoids to treat moderate-to-severe patients, while triple therapy including minocycline for mild and part of moderate patients is effective.
出处
《临床医学工程》
2016年第3期371-372,共2页
Clinical Medicine & Engineering
关键词
大疱性类天疱疮
老年
临床特点
治疗
Bullous pemphigoid
Elderly
Clinical feature
Treatment
