摘要
目的研究小儿腹泻病与T淋巴细胞亚群、血清维生素D3的关系。方法临床纳入143例我院2012年8月至2015年3月期间收治的腹泻患儿作为观察组,另选取120例同期来我院进行体检的健康儿童作为对照组,对两组儿童的T淋巴细胞亚群、血清维生素D3水平进行检查,观察T淋巴细胞亚群、血清维生素D3水平与小儿腹泻的关系。结果观察组的CD3^+、CD4^+、CD4^+/CD8^+水平显著低于对照组,CD8^+水平显著高于对照组,差异有统计学意义(P<0.05)。观察组的维生素D水平为(25.14±6.37)ng/m L,显著低于对照组的(38.41±6.26)ng/m L,差异有统计学意义(P<0.05)。T淋巴细胞亚群、维生素D均是影响小儿腹泻的危险因素,且维生素D水平与T淋巴细胞亚群水平呈正相关。结论对于腹泻小儿需要适当增加维生素D水平,提高患儿的免疫力,提高治疗的效果。
Objective To study the relationships between pediatric diarrhea and levels of T lymphocyte subsets and serum vitamin D3. Methods A total of 143 cases of pediatric diarrhea admitted to our hospital from August 2012 to March 2015 were selected as the observation group, and 120 cases of healthy children with physical examination at the same period were selected as the control group. The levels of T lymphocyte subsets and serum vitamin D3 of two groups were observed and compared. Results The CD3~＋, CD4~＋, CD4~＋/CD8~＋levels of observation group were significantly lower than those of control group, and the CD8~＋level of observation group was significantly higher than that of control group（P〈0.05）. The vitamin D3 level of observation group was（25.14 ± 6.37） ng/m L, significantly lower than（38.41 ± 6.26） ng/m L of control group（P〈0.05）. Both T lymphocyte subsets and vitamin D3 were the risk factors of pediatric diarrhea, and the vitamin D3 level was positively related with levels of T lymphocyte subsets. Conclusions Children with diarrhea should increase vitamin D level, so as to improve immunity of children, and improve the curative effect.
出处
《临床医学工程》
2016年第3期331-332,共2页
Clinical Medicine & Engineering
