摘要
目的:研究并探讨阿立哌唑与利培酮治疗精神分裂症的临床疗效。方法:选取2011年1月-2015年1月收治的100例精神分裂症患者作为研究对象。按照电脑随机抽取的方法将其分为A组(使用利培酮)和B组(使用阿立哌唑),各50例。对患者的疗效进行评估,并观察患者的不良反应发生情况。结果:A组治疗总有效率为88%,B组为92%,两组比较差异无统计学意义(P>0.05)。两组患者均无明显不良反应,但A组患者的体重增长幅度较B组显著,比较差异有统计学意义(P<0.05)。结论:阿立哌唑和利培酮在精神分裂症的治疗中,均具有较为显著的疗效,且安全性较高,但服用利培酮的患者体重增长更加显著。
Objective：To study and discuss the clinical efficacy of Aripiprazole and Risperidone in the treatment of schizophrenia.Method：100 schizophrenia patients were selected as the research object from January 2011 to January 2015,which were divided into A group（using Risperidone） and B group（using Aripiprazole） according to the computer random sampling method,50 cases in each group.The efficacy was evaluated and the adverse reactions of patients were observed.Result：The total effective rate was 88% of the A group,and the total effective rate was 92% of the B group,and the difference was not significant（P0.05）.The two groups of patients had no obvious adverse reaction,but the weight of the A group was more significant increase than the B group,the difference was significant（P0.05）.Conclusion：Aripiprazole and Risperidone in the treatment of schizophrenia have obvious curative effect,and the safety is high,but weight growth is more significant after using Risperidone.
出处
《中外医学研究》
2016年第8期24-25,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
精神分裂症
阿立哌唑
利培酮
疗效
Schizophrenia
Risperidone
Aripiprazole
Curative effect
