摘要
哺乳动物的肠道寄居着大量而且种类繁多的微生物,它们受到宿主基因和环境尤其是食物的影响。近年来,随着宏基因组的出现和测序技术的不断发展,关于人和其他动物的肠道微生物研究日益深入。肠道微生物与人类肥胖和Ⅱ型糖尿病相关性的发现等,进一步加强了科学界对于肠道微生物的关注度。然而,对于肠道微生物与宿主的密切联系以及相互作用机制仍然需要深入研究。本文简要论述了肠道微生物对宿主的功能贡献和宿主的遗传背景对肠道微生物的影响。
The mammalian intestine is colonized with huge number and kinds of microorganisms, which are affected by the host genetics and environment, especially by food. In recent years, with the continuous development of metagenomics and sequencing technologies, there are more and more researches on intestinal microbial of human and other animals. The discovery of connections between intestinal microbes and human obesity or diabetes can enhance the scientific attention community for intestinal microflora communities. However, in-depth studies of the close contacts and the interaction mechanisms with the gut microbiota and host are still needed. This paper briefly discussed some functions of gut microbes on host contributions and effects of the gut microbes by host genetic background.
出处
《中国畜牧杂志》
CAS
北大核心
2016年第5期84-88,共5页
Chinese Journal of Animal Science
基金
北京市现代农业产业技术创新团队(25019126)
国家科技支撑计划(2011BAD28B01)
关键词
肠道微生物
宿主
遗传背景
gut microbiota
host
genetic background
