摘要
目的:探讨腹腔灌注化疗联合内生场热疗治疗胰腺癌恶性腹水的临床疗效。方法:将50例晚期胰腺癌合并恶性腹水患者随机分为实验组与对照组,每组25例。实验组行腹腔灌注化疗联合内生场热疗治疗,对照组单纯行腹腔灌注化疗。比较两组患者腹水控制疗效、生活质量改善、疼痛程度和不良反应情况。结果:实验组患者治疗后腹水控制总有效率为68.0%,明显高于对照组的36.0%(P<0.05);实验组生活质量改善率达60.0%,远高于对照组的40.0%(P<0.05);实验组患者疼痛水平明显好于对照组(P<0.05);两组患者不良反应发生率无明显差异(P>0.05)。结论:腹腔灌注化疗联合内生场热疗治疗胰腺癌恶性腹水效果显著,能明显改善患者生活质量、缓解疼痛,值得临床推广。
Objective： To explore the effect of intraperitoneal chemotherapy combined with endogenetic field thermotherapy in the treatment of malignant ascites and pancreatic cancer. Methods： Divided 50 patients with advanced malignant ascites and pancreatic cancer randomly into experiment group and control group, with 25 patients in each group. The experiment group was treated with intraperitoneal chemotherapy combined with endogenetic field thermotherapy, while the control group was only was treated with intraperitoneal chemotherapy. Compared the effect of ascites control, improvement rate of life quality, pain degree and the incidence of adverse reaction.Results： The total effective rate of ascites control in the experiment group was 68.0%, which was significantly higher than 36.0% in control group（P〈0.05）; The improvement rate of life quality in experiment group was 60%, which was significantly higher than 40% in control group（P〈0.05）; The pain degree in experiment group was significantly better than control group（P〈0.05）; The incidence of adverse reaction in two groups was no significant difference. Conclusion： Intraperitoneal chemotherapy combined with endogenetic field thermotherapy has great effect in the treatment of malignant ascites and pancreatic cancer, it can significantly improve the life quality and relieve pain,which is worth of clinical promotion.
出处
《现代生物医学进展》
CAS
2016年第1期88-90,共3页
Progress in Modern Biomedicine
关键词
腹腔灌注化疗
内生场热疗
胰腺癌
恶性腹水
效果
Intraperitoneal chemotherapy
Endogenetic field thermotherapy
Pancreatic cancer
Malignant ascites
Effect
