摘要
目的观察并分析宫颈癌筛查中液基细胞学检查和高危HPV筛查(HC-2方法)的临床价值。方法将2014年3月至2015年3月1400例宫颈癌筛查病例纳入本次研究,入组患者均接受宫颈液基细胞学检测以及高危型HR-HPV检测,其中检测结果异常者均采取病理组织活检,参照病理活检结果评估筛查结果。结果宫颈液基细胞学检测结果提示异常率为12.9%(174/1400);HPV阴性组患者平均年龄明显高于HPV阳性组平均年龄,差异具有统计学意义(P<0.05);随着病理学以及细胞学诊断级别逐步提升,HPV感染率也显著升高(P<0.05)。结论在诸多宫颈癌筛查方法中,宫颈液基细胞学检查与高危型人乳头瘤病毒检测联合筛查方案是有效且可靠的,其对于宫颈高度病变以及高危人群的确诊率较高,对宫颈癌的发生有预防作用,具有积极的临床意义。
Objective 1400 cases of patients who received cervical cancer screening during March 2014 to March 2015 were selected as the study objects,enrolled patients received liquid- based cervical cytology and high- risk HR- HPV testing,those with abnormal test results took pathological biopsy,and the assessment of screening results were according to the biopsy results.Results Cervical cytology test results showed abnormal rate was 12.9%（ 174 /1400）; The average age of patients in HPV- negative group was significantly higher than that in HPV- positive group,there was statistical significance（ P 0.05）.As the pathology and cytology level increased gradually,HPV infection rates were significantly increased（ P 0.05）.Conclusions In the numerous cervical cancer screening methods,liquid- based cervical cytology and high- risk human papillomavirus detection combined screening program is efficient and reliable,it has high diagnosis rate for high-grade cervical lesions and high- risk groups,and has preventive effect to cervical cancer,with positive clinical significance.
出处
《齐齐哈尔医学院学报》
2016年第3期286-287,共2页
Journal of Qiqihar Medical University
关键词
宫颈癌筛查
人乳头瘤病毒
液基细胞学
Cervical cancer screening
Human papillomavirus
Liquid-based cytology
