摘要
目的通过眼表观察比较两种翼状胬肉手术的临床效果。方法选取76例原发翼状胬肉患者随机分成AB2组,各38人。A组采取翼状胬肉切除联合术中使用丝裂霉素C;B组采取翼状胬肉切除联合带自体角膜缘干细胞的结膜移植。比较2组患者的泪膜破裂时间(BUT),复发率,角膜修复时间、形态,术后不适症状的改善。结果 2组患者角膜修复行为不同。2组患者于术后一周观察角膜上皮修复程度,B组好于A组(P<0.05);2组患者BUT比较,A组术前与术后无显著性差异(P>0.05);B组术前与术后有显著性差异(P<0.05);A、B两组术后6个月泪膜破裂时间,B组较A组更长(P<0.05);2组术后6个月眼部干涩、异物感等症状改善比较无显著性差异(P>0.05);术后6个月复发率比较无显著性差异(P>0.05)。结论翼状胬肉切除联合自体带角膜缘干细胞的结膜移植术后角膜上皮修复快,泪膜稳定性有明显提高。
Objetive To compare the clinical effect of two kinds of pterygium surgery based on the eye surface observation.Methods 76 cases of primary pterygium were selected and divided into 2 groups A and B randomly, each of them included 38 cases. In group A, cases underwent pterygium excision combined use of mitomycin C intraoperatively; In group B, cases underwent pterygium excision combined with limbal conjunctival and its stem cells autograft. Break-up time（BUT）, recurrence rate, time and shape of the cornea restoration, and the improvement of postoperative symptoms were recorded and compared. Results Corneal restorations of two groups acted differently. A week later, for corneal epithelium restoration,group B was better than group A（P〈0.05）; There was no significant difference（P〉0.05） for BUT between preoperative and postoperative of group A, but there was significant difference for that of group B（P〈0.05）; There was significant difference of BUT between group A and B after 6 months（P〈0.05）; After 6 months, there was no significant difference for improvement of the symptom such as dry eye, foreign body sensation（P〉0.05） and recurrence（P〉0.05）. Conclusion Pterygium excision combined with limbal conjunctival and its stem cells autograft makes patient＇s corneal epithelium repair faster and the tear film stability improve obviously.
出处
《实用防盲技术》
2016年第1期28-30,6,共4页
Journal of Practical Preventing Blind
