摘要
目的综述脂肪来源干细胞(adipose-derived stem cells,ADSCs)复合3D打印支架在脂肪、骨、软骨、血管、肝细胞等组织工程领域的研究进展。方法广泛查阅近年国内外与ADSCs复合3D打印支架构建工程化组织研究相关的文献,并进行总结分析。结果研究表明,ADSCs可在3D打印支架中分化成多种组织细胞,参与促进各种损伤修复再生,但相关研究尚处于早期阶段。结论利用ADSCs与3D打印支架构建工程化组织有望修复脂肪、骨、软骨等损伤组织器官结构并重建功能。
Objective To review the research progress of adipose-derived stem cells (ADSCs) compound with three dimensional (3D) printing scaffold in tissue engineering of fat, bone, cartilage, blood vessel, hepatocyte, and so on. Methods The recently published literature about ADSCs compound with 3D printing scaffold in tissue engineering at home and abroad was reviewed, analyzed, and summarized. Results A large number of basic researches showed that ADSCs could differentiate into a variety of tissues on 3D printing scaffold and involve in tissue repair and regeneration. But there is still a long way between the basic theory and the clinical practice at the early stages of development. Conclusion It can effectively improve and restore the structure and function of the damaged tissue and organ to use ADSCs and 3D printing scaffold.
出处
《中国修复重建外科杂志》
CAS
CSCD
北大核心
2016年第3期320-322,共3页
Chinese Journal of Reparative and Reconstructive Surgery
关键词
脂肪来源干细胞
3D打印
生物支架
组织工程
Adipose-derived stem cells
Three dimensional printing
Biological scaffold
Tissue engineering