摘要
目的分析健康人尿液结晶形成条件,探寻尿石症（USD）产生原因。方法在连续一年中收集到健康志愿者600余次尿液,测定每份尿液的pH值、比重、尿量和观察尿液有无浑浊结晶;探寻尿指标改变与结晶析出之间的相关性。结果尿液中出现结晶物与尿液pH升高有密切关系P〈0.001,与尿比重和尿量没有统计学意义P〉0.05。尿液pH在5.5~5.9范围时,尿液清澈透明;尿液pH升高至6.0~6.5范围时,尿中出现结晶的概率约为0.4%;尿液pH值升高至6.6~7.0时,尿中出现结晶的概率上升了100倍,达到40.5%;尿液pH值升高至7.1~7.5时,尿中出现结晶的概率再翻一番至85.2%。结论对健康人而言,尿液pH改变是产生尿结晶的重要诱因,而结晶物析出是生成USD的前提条件;维持尿液pH在5.5~6.5是预防USD的有效范围;尿液pH升高至6.6以上,随pH值升高发生USD的危险程度成正比升高。
Objective To explore causes of the formation of urinary stone disease（USD）by analyzing the formation condition of urine sediment crystal in healthy people.Methods A total of 600 urine samples were collected from healthy volunteers in one year to observe the turbidity and urine sediment crystal after the pH value,density and volume were measured.The correlation between changes of urine indexes and crystallization was analyzed.Results The formation of urine crystal was closely associated with the pH value（P〈0.001）,but not with the density or volume（P〉0.05）.When the pH value was between 5.5 and 5.9,the urine was clear.The probability of having urine crystal was 0.4% when the pH value was between6.0and 6.5.The probability of having urine crystal increased a hundred times,up to 40.5% when the pH value was between 6.6and7.0.The probability of having urine crystal reached85.2% when the pH value was between7.1 and7.5.Conclusion For healthy people,the change of pH value of urine is only incentive of having urine crystal,and crystallization of urine crystal is the prerequisite of USD formation.In order to prevent USD,the best range of urine pH value is 6.0-6.5.When it is higher than6.6,the probability of having USD is proportional to the increase of pH value.
出处
《现代泌尿外科杂志》
CAS
2016年第2期143-146,共4页
Journal of Modern Urology
基金
贵阳中医学院学术带头人项目基金(No.中医学科合字XKMB[2015]106)
关键词
尿石症
尿液pH
尿比重
尿量
尿结晶
urinary stone disease
pH value of urine
density of urine
volume of urine
urine crystal
