摘要
目的研究孟鲁司特钠与丙卡特罗相结合治疗儿童慢性咳嗽的临床疗效以及对患儿血清中IgE水平的影响.方法：随机选取门诊接诊治疗的慢性咳嗽儿童患者90例,根据其临床治疗方式的不同随机分为研究组和对照组,45例研究组患儿通过孟鲁司特钠联合丙卡特罗进行治疗,45例对照组患儿通过丙卡特罗进行治疗,连续治疗4周,对比两组患儿慢性咳嗽症状的改善情况以及血清IgE水平水平变化.结果：两组患儿经过4周治疗后,慢性咳嗽临床症状均有所改善、血清IgE水平均有所降低（P〈0.05）,但研究组患儿慢性咳嗽症状症状缓解和消失所用时间短于对照组患儿,血清IgE水平降低幅度大于对照组患儿,组间比较差异显著具有统计学意义（P〈0.05）;研究组患儿临床治疗有效率为93.33%（42/45）,显著高于对照组68.89%（31/45）的临床治疗有效率（P〈0.05）.结论：孟鲁司特钠联合丙卡特罗治疗小儿慢性咳嗽起效快、疗效显著,可有效降低患儿血清IgE水平.
Objective Study the clinical efficacy of montelukast sodium and procaterol for treating the patient with chronic cough and its impact On serum immunoglobulin E. Methods： There are 90 patients which are patients in our clinic from January 2014 to January 2015 for treatment being selected. They were randomly divided into study and control groups in these patients depending on their clinical treatment modalities. 45 patients of study group cases of children with montelukast sodium by joint procaterol treatment, 45 cases in the control group were treated by procaterol. After four weeks of continuous treatment, compared two groups of patients to improve the situation of chronic cough and serum changes in the level of IgE levels. Results： After four weeks of continuous treatment, Two groups of patients with chronic cough symptoms were improved, serum IgE levels were decreased. However, The patients of study group with chronic cough symptoms and disappearance time spent shorter than the control group of patients, a reduction in serum IgE levels greater than children in the control group, significantly between the two groups was statistically significant difference （P 〈0.05）; The patients of study group with clinical effective rate was 93.33% （42/45）, significantly higher than 68.89% （31/45） of clinical effectiveness （P 〈0.05）. Conclusions： Montelukast combined procaterol to treatment the patients with chronic cough procaterol have a rapid onset, a significant effect, can effectively reduce serum IgE levels.
出处
《世界中医药》
CAS
2015年第A02期997-998,共2页
World Chinese Medicine
