摘要
目的研究将GM和1-3-β-D葡聚糖抗原检测应用于IFD（侵袭性真菌感染）诊断中的临床价值.方法：抽取我院2014年9月～2015年8月住院的疑似IFD病人120例,按照诊断标准核实病人的诊断情况,进行GM试验和G试验后对比两组试验单独进行和联合使用的诊断特异度及敏感度.结果：G试验应用效果：临界值为20 pg/mL时,G试验可达到52.27%的灵敏度,90.79%的特异度;GM试验应用效果：临界值为0.5时,GM试验可达到68.18%的灵敏度,81.58%的特异度;两组试验联合使用的诊断效果：可达到93.18%的灵敏度,77.63%的特异度,联合使用的诊断效果明显优于任-种单-试验.结论：G 试验和GM 试验对IFD均有较好的诊断价值,如果将两种试验联合应用,则会使之临床应用价值更高.
Objective to study the GM and 1-3 - beta glucan D antigen detection is applied to IFD （invasive fungal infection） in the diagnosis of clinical value. Method： extract from September 2014 to August 2015, 120 cases of suspected IFD in hospital patients, according to the diagnostic criteria to verify the patient＇s diagnosis, GM after experiment and G compared two groups of test with independently from the combination of diagnostic and sensitivity. Results： G test application effect of the critical value of 20 pg/mL, G test can reach 52.27%, the sensitivity of the 90.79% of the specific degree; GM test application effect： when the critical value of 0.5, the sensitivity of GM test can achieve 68.18%, 81.58% of the specific degree; Combination of two groups of test used in the diagnosis of effect： the sensitivity of 93.18%, 77.63% of the specific degree, combination of diagnosis effect is superior to any single test. Conclusion： G experiment and GM of IFD has the better diagnostic value, if the two kinds of test joint application, will make a higher clinical value.
出处
《世界中医药》
CAS
2015年第A02期835-836,共2页
World Chinese Medicine
