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老年人髋部骨折术后急性期谵妄和脑脊液神经元特异性烯醇化酶、乳酸水平的相关性 被引量:4

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摘要 目的探讨老年人髋部骨折术后谵妄和脑脊液神经元特异性烯醇化酶(NSE)、乳酸(Lactate)水平高低是否存在相关性。方法回顾性研究老年人髋部骨折采取脊髓麻醉并手术治疗共138例,采集术前脑脊液样本并测定其NSE、Lactate的水平。并通过对患者家属或照顾者的老年人认知功能减退问卷(IQCODE-SF)~9[1])评估骨折前的认知功能水平。术后急性期谵妄诊断标准是谵妄评定方法(Confusion Assessment Method,CAM)[2],并以此分为谵妄组和非谵妄组。结果老年人髋部骨折术后急性期发生谵妄的发生率为40.6%。谵妄组病人脑脊液的NSE、Lactate的水平要明显高于非谵妄组(P〈0.05)。结论老年人髋部骨折术后急性期谵妄和脑脊液的NSE呈负相关,与Lactate水平呈正相关。
出处 《浙江创伤外科》 2016年第1期104-106,共3页 Zhejiang Journal of Traumatic Surgery
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  • 1Jorm AF:A short form of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) :development and cross-validation [J]. Psychol Med 1994; 24:145-153. 被引量:1
  • 2Inouye SK,van Dyck CH,Alessi CA,et al. Clarifying confusion:the confusion assess- ment method a new method for detection of delirium[J]. Ann Intern Med 1990;113: 941-948. 被引量:1
  • 3Slor CJ,Adamis D,Jansen RW,et al. Delirium motor subtypes in elderly hip fracture patients :risk factors,outcomes and longitudinal stability [J].J Psychosom Res, 2013,74 : 444-449. 被引量:1
  • 4Smith Smith T, Hammeed Y, Cross J, et al. Assessment of people with cognitive im- pairment and hip fracture:as ystematic review and meta-analysis[J]..Arch Geron- tol Geriatr,2013,57 : 117-126. 被引量:1
  • 5Rudolph Rudolph JL,Marcantonio El/. Review articles : postoperative delirium : a- cute change with long-term implication [J]..Anesth Analg,2012,112 : 1202-1211. 被引量:1
  • 6Maldonado JR.Pathoetiological model of delirium:a comprehensive understanding of the neurobiology of delirium and an ev- idence-based approach to prevention and treatment [J]. Crit Care Clin 2008,24: 789-856. 被引量:1
  • 7Ix. Cunningham C, Maclullich AM.At the ex- treme end of the psychoneuroimmunologi- cal spectrum:delirium as a maladaptive sickness behaviour response[J]. Brain Be- hay Immun 2013,28 : 1-13. 被引量:1
  • 8Cerejeira J,Firmino H,Vaz-Serra A,et al. The neuroinflammatory hypothesis of delirium. Acta Neuropathol 2010,119: 737-754. 被引量:1
  • 9Maldnodo J l/.Pathoetiological model of defirium:a comprehensive understanding of the neurobiology of delirium and an ev- idence-based approach to prevention of treatment[J]..Crit Care Clin ,2008,24 (4) : 789-856. 被引量:1
  • 10Hshieh TT,Fong TG,Marcantonio El/,et al.Cholinergic deficiency hypothesis indelirium:a synthesis of current evidence [J].J Gerontol A Biol Sei Med Sei,2008: 63 : 764-72. 被引量:1

二级参考文献19

  • 1罗林枝,徐苓.骨质疏松性髋部骨折的直接经济负担及其影响因素分析[J].中华流行病学杂志,2005,26(9):669-672. 被引量:39
  • 2Foreman MD, Milisen K. Improving recognition of delirium in the elderly. Primary Psychiatry,2004,11~ 46-50. 被引量:1
  • 3Wei LA, Fearing MA, Sternberg EJ, et al. The confusion assessment method: a systematic review of current usage. J Am Geriatr Soc, 2008, 56:823-830. 被引量:1
  • 4SiddJqi N, House AO, Holmes JD. Occurrence and outcome of delirium in medical in- patients: a systematic literature review. Age Ageing, 2006,35 350-364. 被引量:1
  • 5Catic AG. Dentiflcation and management of in- hospital drug-induced delirium in older patients. Drugs Aging, 2011,28 : 737 748. 被引量:1
  • 6Cole MG, Ciampi A, Belzile E, et al. Persistent delirium in older hospital patients: a systematic review of frequency and prognosis. Age Ageing, 2009, 38:19-26. 被引量:1
  • 7Nikkei LE, Fox EJ, Black KP, et al. Impact of comorbidities on hospitalization costs following hip fracture. J Bone Joint Surg Am, 2012, 94 : 9-17. 被引量:1
  • 8Chen LT,Lee JA, Chua BS,et al. Hip fractures in the elderly . the impact of comorbid illnesses on hospitalisation costs. Ann Acad Med Singapore, 2007, 36:784-787. 被引量:1
  • 9Bouee S,Lafuma A,Fagnani F,et al. Estimation of direct unit costs associated with non-vertebral osteoporotic fractures in five European countries. Rheumatol Int,2006,26 : 1063-1072. 被引量:1
  • 10Cummings SR,Melton LJ. Epidemiology and outcomes of osteoporotic fractures. Lancet, 2002, 359: 1761-1767. 被引量:1

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