摘要
目的探讨麻疹并发肝损害的临床特征、肝功情况、严重程度、预后。方法整群选取该院2013年1月—2014年12月收治的97例住院确诊的麻疹患者为研究对象,按肝功能、肝炎血清标志物检查作出并发肝损害诊断,并根据肝功丙氨酸氨基转移酶、总胆红素、白蛋白情况将肝损害分为轻、中、重度,对患者发热、皮疹、消化道症状等与肝损害程度的关系进行回顾性分析。结果 97例麻疹患者中44例并发肝损害,占入选病例的45.36%。其中成年人35例,占肝损害患者比例79.55%。所有患者均有不同程度的消化道症状。患者肝损害均发生于出疹期;轻度肝损害14例,中度肝损害22例,重度肝损害8例。肝功能提示以丙氨酸氨基转移酶、天冬氨酸氨基转移酶(AST)、γ-谷氨酰转肽酶(GGT)升高为主,较少见总胆红素增高。患者肝功能随麻疹病情好转而恢复正常,无慢性化倾向。结论麻疹合并肝功能损害成年人较常见,多发生于出疹期,且程度一般为轻中度,预后良好。
Objective To discuss the clinical characteristics, hepatic function, severity and prognosis of measles complicated by hepatic !lesion. Methods 97 cases of measles patients confirmed in hospital from January 2013 to December 2014 were diagnosed with concurrent hepatic lesion according to hepatic function and serum markers of hepatitis examination, the hep- atic lesion was divided into mild, moderate and severe according to the conditions of liver alanine aminotransferase, total bilirubin and albumin, the relationship between fever, rash and digestive tract symptom in patients and degree of hepatic lesion was retrospectively analyzed. Results 44 cases were complicated by hepatic lesion in the 97 cases of measles patients, accounting for 45.36% of the selected cases, among them, the adults were 35 cases, accounting for 79.55% of the patients with hepatic lesion, all patients had different degrees of digestive tract symptoms, hepatic lesion in patients occurred in the eruptive stage, 14 cases were mild, 22 cases were moderate and 8 cases were severe, hepatic function indicated that the increase of AAT, AST and GGT was the main and the increase of total bilirubin was less, the patient＇s hepatic function recovered to normal with the improvement of the measles and there was no chronicity tendency. Conclusion Measles complicated by hepatic lesion was common in adults, most occurred in the eruptive stage, mild and moderate were in general and the prognosis is good.
出处
《中外医疗》
2015年第35期43-45,共3页
China & Foreign Medical Treatment
关键词
麻疹
肝损害
Measles
Hepatic lesion
