摘要
目的探讨近10年国外慢性肝病肝纤维化诊断方法的研究状况。方法对近10年已发表在Pub Med、Embase、Web of science中有关慢性肝病肝纤维化诊断方法的英文文献进行检索,运用Endnote X7、Bicomb 2.0软件进行文献计量学分析。将出现频次不小于40次的有关肝纤维化诊断方法的关键词作为高频主题词,进行共词聚类分析。结果共检索出有效文献1 253篇,文献年发表量大致呈上升趋势。有关肝纤维化诊断方法的关键词5 767个,出现频率最高的高频关键词依次为肝活检、生物化学指标及超声弹性成像技术。结论肝活检病理检查仍是肝纤维化诊断的参考标准,血清生物化学指标是肝纤维化的常用检测手段。以超声为基础的肝脏弹性测定技术现已经成为肝纤维化无创诊断的主要方法。
Objective To explore the research situation in abroad of liver fibrosis in chronic liver disease the last ten years. Methods The English literatures which were involved in liver fibrosis diagnosis from 1995 to 2014 have been retrieved on PuhMed, Embase, Web of science. The bibliometrie analysis has been operated with Endnote XT, Bicomh2. 0 software. The high frequency keywords of liver fibrosis diagnostic test have been defined by the frequency not less than 40. At last, the high frequency key-words have been put into SPSS20. 0 and made cluster analysis. Results A total of 1 253 available literatures have been screened, roughly the amount of literatures published on the rise. The 5 767 key words of liver fibrosis diagnostic test have been screened. The most frequent key words are biopsy, biological markers and elastography in the order. Conclusion Biopsy is still the diagnostic reference standard of liver fibrosis. Serological examination is common testing method. Imaging, especially ultrasonic elasticity measurement has been major noninvasive diagnostic means.
出处
《首都医科大学学报》
CAS
北大核心
2016年第1期83-88,共6页
Journal of Capital Medical University
基金
国家中医药管理局中医预防医学重点培育学科建设项目[(2012)170]~~
关键词
肝纤维化
诊断
文献计量学
liver fibrosis
diagnosis
bibliometric analysis
