摘要
目的 探讨西格列汀治疗老年2型糖尿病的疗效. 方法 整群选取2014年1月1日—2015年5月31日入该院的糖尿病患者158例. 随机分为对照组和观察组各79例. 对照组给予胰岛素治疗,观察组在对照组的基础上给予西格列汀治疗,观察两组的餐后2 h的血糖（2 hPG） 、空腹血糖（ FPG） 和糖化血红蛋白（ Hb Alc） 水平. 结果 两组治疗前后2 h PG、FPG、HbAlc比较,三者水平均下降. 将两组治疗后2hPG、FPG、HbAlc的水平分别比较,差异有统计学意义（P〈0.05）. 观察组的总不良反应发生率比对照组低,治疗后总不良反应发生率对比,差异有统计学意义（χ2=13.19,P〈0.05）. 结论 西格列汀联合胰岛素有助于降低糖尿病患者的血糖水平.
Objective To observe the efficacy of sitagliptin in treating elderly patients with type 2 diabetes. Methods 158 patients with diabetes admitted to this hospital from January 1, 2014 to May 31, 2015 were included and randomly divided into control group and observation group with 79 in each one. The control group was treated with insulin, while the observa-tion group, based on the control group, was treated with sitagliptin. The level of 2-hour postprandial plasma glucose （2hPG）, fasting blood glucose （FPG）, and glycosylated hemoglobin （HbAlc） of the two groups were observed. Results The level of 2hPG, FPG, HbAlc decreased in both of the two groups after treatment. There was statistically significant difference in the level of 2hPG, FPG, HbAlc between the two groups after treatment,（P〈0.05）. The total adverse reaction rate was lower in the observation group than in the control group, and the difference was statistically significant, （χ2=13.19, P〈0.05）.Conclusion Sitagliptin combined with insulin is conducive to reducing the blood glucose level in patients with diabetes.
出处
《中外医疗》
2015年第32期140-141,共2页
China & Foreign Medical Treatment
关键词
西格列汀
2型糖尿病
胰岛素
Sitagliptin
Type 2 Diabetes Mellitus
Insulin
