摘要
目的探讨两种手术治疗对精索静脉曲张患者血清免疫球蛋白浓度及预后的不同影响,为精索静脉曲张治疗方法的选择提供依据。方法将88例原发性精索静脉曲张患者根据手术方法分为显微镜组(n=44)和腹腔镜组(n=44)。比较两组疗效、手术时间、术后住院时间、围术期血清免疫球蛋白浓度、并发症发生及术后12个月的复发情况。结果显微镜组手术时间为(54.69±8.59)min,长于腹腔镜组的(35.97±7.15)min,差异有统计学意义(P<0.05)。与腹腔镜组比较,显微镜组T_2和T_3的血清免疫球蛋白浓度升高,差异有统计学意义(P<0.05)。显微镜组并发症总发生率和术后12个月复发率分别为2.27%和2.27%,均低于腹腔镜组的20.45%和18.18%(P<0.05)。结论显微镜下行精索静脉高位结扎术治疗精索静脉曲张可更有效提高患者免疫功能和改善其预后,可行性和安全性较高,值得临床推广使用。
Objective To investigate the impact on serum immunoglobulin concentrations and prognosis of two kinds of surgical method treating patients with varieocele, and provide evidence for the choice of varicocele treatment. Methods 88 patients with varicocele were divided into microscope group （n=44） and laparoscopic group （n=44） based on the treating method. Curative effect, operation time and postoperative hospital stay, perioperative serum immunoglobulin concentrations, complications and postoperative 12 months recurrence rate of two groups were compared. Results Operation time of microscope group was （ 54.69±8.59 ） min, which was significantly longer than that （ 35.97±7.15 ） min of the laparoscopic group （P〈0.05）. Compared with the laparoscopic group, T2 and T3 serum immunoglobulin concentrations of microscope group was significantly elevated （P〈0.05）. Total incidence of complications and postoperative 12 months recurrence rates of microscope group were 2.27% and 2.27%, respectively, which were lower than those （20.45% and 18.18% ） of the laparoscopic group （P〈0.05）. Conclusions Spermatic vein high ligation under microscope can more effectively improve the patients＇ immune function and prognosis, thus it can gain good curative effect and safety and is worthy of clinical promotion.
出处
《热带医学杂志》
CAS
2016年第1期78-81,共4页
Journal of Tropical Medicine
