摘要
目的探讨临产妇预防性使用间苯三酚的临床价值:是否可以减少宫颈水肿的发生,是否可以缩短第一产程等等。方法选择武警总医院2014-02至2014-11孕足月、单胎、头位初孕妇共100例作为试验组,试验组在出现规律宫缩后,即给予间苯三酚80 mg静推1次/2 h,鉴于间苯三酚日最大剂量的影响,每天最多推2次。同期选择100例孕妇作为对照组。对照组未给予任何处置,任其产程自然进展。比较两组第一产程、第二产程、第三产程时间,宫颈水肿的发生人数,中转剖宫产人数,产后2 h出血量,新生儿Apgar评分。结果试验组第一产程较对照组明显缩短,差异有统计学意义(P<0.05)。第二产程、第三产程差异无统计学意义。试验组宫颈水肿4例,对照组16例,差异有统计学意义(P<0.05)。试验组、对照组分别有16例和29例产妇试产失败后转为剖宫产,两组比较差异有统计学意义(P<0.05)。产后2 h出血量,新生儿Apgar评分两组比较无显著差异。结论间苯三酚为安全解痉药物,可早期预防性应用。本研究证实,临产妇预防性使用间苯三酚可以有效降低宫颈水肿的发生率,缩短第一产程,降低剖宫产率,且对母儿无不良影响。
Objective To study the clinical value of prophylactic use of phloroglucinol in the incubation period. Methods From February 2014 to November 2014, a total of 100 full-term pregnant, monocyesis and primigravid women were recrui- ted as study group, after regular contractions developed, they were given phloroglucinol 80 mg intravenously every 2 hours, twice a day at most . At the same time another 100 pregnant women were recruited as control group; they did not receive any disposal and et the la- bor naturally progress. Between two groups, the first, second and third stages of labor time, number of patients with cervix edema, transter number of cesarean section, 2 h bleeding roluml after delivery, neonatal Apgar score were compared. Results The first stage of labor in the study group was shortened obviously, the difference was statistically significant （ P 〈 O. 05 ）. The second and third stages of labor bad no statistically significant difference （ P 〈 O. 05 ）. the cervix edema developed in 4 cases in the study group , 16 cases in the control group, the difference was statistically significant. In the study group and control group, 16 cases and 29 cases failed and turned to cesarean section ; the difference was significant between the two groups （ P 〈 0.05 ）. 2 h postpartum blood loss and neonatal Apgar score between the two groups were to significantly different. Conclusion Phloroglucinol as a safe spasmolytic medicine, also can be applied to the early clinical stage for prevention. This study confirmed that preventive use of phloroglucinol in the incubation pe- riod can effectively reduce the incidence rate of cervix edema, shorten the first stage of labor and reduce cesarean delivery rate ; and has no adverse effect on mother and fetus.
出处
《武警医学》
CAS
2016年第1期15-17,共3页
Medical Journal of the Chinese People's Armed Police Force
关键词
间苯三酚
临产妇
phloroglucinol
the incubation period
