摘要
目的对比大动脉粥样硬化型脑梗死与穿支动脉疾病型脑梗死的临床特征。方法选择重庆市万州区人民医院2012年3月—2015年3月收治的60例大动脉粥样硬化型脑梗死患者作为A组,60例穿支动脉疾病型脑梗死患者作为B组。比较两组患者一般资料、实验室检查指标及基础疾病等。结果两组患者性别、年龄及原因不明者所占比例比较,差异无统计学意义(P>0.05);A组患者吸烟率、饮酒率高于B组(P<0.05)。A组患者血浆氧化低密度脂蛋白(ox-LDL)水平及循环内皮细胞计数高于B组,血浆一氧化氮(NO)水平低于B组(P<0.05)。两组患者高血压发生率比较,差异无统计学意义(P>0.05);A组患者冠心病、脂代谢异常发生率高于B组,糖尿病发生率低于B组(P<0.05)。结论与穿支动脉疾病型脑梗死患者相比,大动脉粥样硬化型脑梗死患者吸烟率、饮酒率、血浆ox-LDL水平、循环内皮细胞计数及冠心病、脂代谢异常发生率较高,血浆NO水平及糖尿病发生率较低。
Objective To compare the clinical features between artery atherosclerotic cerebral infarction and perforators artery disease- induced cerebral infarction. Methods From March 2012 to March 2015 in the People＇ s Hospital of Wanzhou District,Chongqing,a total of 60 patients with artery atherosclerotic cerebral infarction were selected as A group,a total of 60 patients with perforators artery disease- induced cerebral infarction were selected as B group. General information,laboratory examination index and underlying disease were compared between the two groups. Results No statistically significant differences of gender,age or proportion of patients with unknown aetiology was found between the two groups（ P〉0. 05）,while smoking rate and drinking rate of A group were statistically significantly higher than those of B group（ P〈0. 05）. Plasma ox-LDL level and circulating endothelial cell count of A group were statistically significantly higher than those of B group,while plasma NO level of A group was statistically significantly lower than that of B group（ P〈0. 05）. No statistically significant differences of incidence of hypertension was found between the two groups（ P〉0. 05）,incidence of coronary heart disease and dyslipidemia of A group was statistically significantly higher than that of B group,respectively,while incidence of diabetes of A group was statistically significantly lower than that of B group（ P〈0. 05）. Conclusion Compared with patients with perforators artery disease- induced cerebral infarction,the smoking rate,drinking rate,plasma ox-LDL level,circulating endothelial cell count,incidence of coronary heart disease and dyslipidemia are significantly higher, while plasma NO level and incidence of diabetes are significantly lower.
出处
《实用心脑肺血管病杂志》
2016年第1期98-100,共3页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
关键词
脑梗死
动脉粥样硬化
穿支动脉疾病
疾病特征
Brain infarction
Atherogenesis
Perforators artery disease
Disease attributes
