摘要
目的:探讨重组人干扰素α-2b凝胶治疗慢性宫颈炎的临床效果。方法:选择2013年6月-2015年4月笔者所在医院妇科的240例慢性宫颈炎患者,随机分为对照组和试验组,试验组采用重组人干扰素α-2b凝胶进行治疗,对照组患者采用普通壳聚糖妇科凝胶进行治疗,治疗6个疗程后,比较两组患者的临床指征、疗效和不良反应。结果:试验组总有效率明显高于对照组(85.0%vs 58.3%,P<0.05),且试验组临床指征在治疗后有明显改善,效果好于对照组,差异有统计学意义(P<0.05)。在治疗过程中,两组患者均未出现明显不良反应。结论:重组人干扰素α-2b凝胶在治疗慢性宫颈炎时临床效果较好,能有效改善患者临床症状,安全性较高,值得推广使用。
Objective：To investigate the clinical effect of recombinant human interferon α-2b in the treatment of chronic cervicitis.Method：240 cases of chronic cervicitis in our hospital from June 2013 to April 2015 were randomly divided into the treatment group（n=120） and the control group（n=120）.The control group was treated by chitosan gel,the treatment group was treated by recombinant human interferon α-2b.After the six course,the clinical indications,efficacy and adverse reactions in two groups were compared.Result：The clinical total effective rate of 85.0% in the treatment group was significantly higher than that of 58.3% in the control group,which had a significant difference between two groups（P〈0.05）.After treatment,clinical indications in the treatment group had obvious improvement compared with the control group（P〈0.05）, in the process of treatment,two groups of patients had no obvious adverse reactions.Conclusion：Recombinant human interferon α-2b in the treatment of chronic cervicitis can significantly improve the symptoms and clinical effect is better,it is worthy of clinical popularization.
出处
《中外医学研究》
2016年第4期7-9,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
