摘要
目的研究糖化血红蛋白（HbA_（1c））与血糖水平在急性心肌梗死患者行经皮冠状动脉介入治疗（PCI）的预后价值。方法选择2012月1月~2013年12月在河北省沧州市人民医院接受接受PCI术治疗的急性心肌梗死患者125例。根据HbA_（1c）以及餐后2 h血糖水平将其分为观察组（HbA_（1c）〉6.5%）67例和对照组（HbA_（1c）≤6.5%）58例;对比两组患者临床患病情况、HbA_（1c）等水平、治疗后心血不良事件发生以及LVDd、LVEF水平。结果观察组糖尿病、多支动脉病变以及陈旧性心肌梗死患者的比例显著高于对照组;观察组HbA_（1c）、餐后2 h血糖、TG水平均显著高于对照组;观察组治疗后再发心肌梗死、心源性休克以及频发室性期前收缩发生比例显著高于对照组;观察组治疗后3个月LVDd高于对照组,而LVEF水平低于对照组;差异均有统计学意义（均P〈0.05）。结论急性心肌梗死患者行PCI术时HbA_（1c）与血糖水平偏高容易升高心血管事件的发生率,同时并发糖尿病、多支动脉病变的概率更大。临床上采用HbA_（1c）与血糖水平具有较高的预后价值,值得推广应用。
Objective To explore the prognostic value of HbA_（1c） and blood glucose levels in patients with acute myocardial infarction（AMI） by percutaneous coronary intervention（PCI）. Methods 125 patients with acute myocardial infarction treated by PCI from January 2012 to December 2013 in Cangzhou People＇s Hospital were selected from patients with acute myocardial infarction. According to the HbA_（1c） and postprandial 2 h blood glucose levels, 125 patients were divided into the observation group（HbA_（1c） 6.5%） of 67 cases in control group（HbA_（1c） of 6.5% or less） 58 cases; The clinical prevalence, HbA_（1c） and LVEF and LVDd levels were compared between two groups. Results The proportion of patients with diabetes, multiple arterial diseases and old myocardial infarction in the observation group were significantly higher than those in the control group. The levels of HbA_（1c） , postprandial 2 h blood glucose and TG in the observation group were significantly higher than those in the control group. The observation group was significantly higher than the control group in the treatment of recurrent myocardial infarction, cardiac shock, and the incidence of premature ventricular contraction. There was no difference in LVDd and LVEF levels in the two groups, and the LVEF was higher than the control group at 3 months after treatment, but the level of LVDd was lower than that in control group.The difference was statistically significant（P〈0.05）. Conclusion The HbA_（1c） and blood glucose levels in patients with acute myocardial infarction were more likely to increase the incidence of cardiovascular events, and the risk of concurrent diabetes and multiple arterial diseases were more likely to occur in patients with acute myocardial infarction. The clinical use of HbA_（1c） and blood glucose levels have a high prognostic value, it is worth promoting the application.
出处
《中国医药导报》
CAS
2016年第5期63-66,共4页
China Medical Herald
基金
河北省沧州市科技计划项目(131302108)
关键词
急性心肌梗死
皮冠状动脉介入术
糖化血红蛋白
血糖水平
预后价值
Acute myocardial infarction
Percutaneous coronary intervention
Glycosylated hemoglobin
Blood glucose level
Prognostic value
