摘要
筛板位于视盘处，由巩膜末端呈筛网状的纤维结缔组织所构成，在视网膜神经纤维通过视盘时为其提供结构上与营养上的支持。许多研究均发现视神经纤维损伤的起始部位是在筛板水平，所以筛板的检查有重要的临床意义，而且对筛板的研究受到极大重视。随着OCT技术的发展，目前已有多种OCT技术能在活体无创的条件下获取筛板的成像信息，如筛板的深度、筛板的厚度以及筛板的微结构改变等。评估这些信息可以间接反映青光眼和眼外伤等的损害情况，为这些眼部疾病的早期诊断、病情评估以及治疗预后提供有效的手段。本文就对筛板进行清晰成像的OCT相关技术及其研究成果做一综述。
The lamina cribrosa is a sieve-like connective tissue beams located in the optic disc and the end of sclera, providing structural and nutritional support to the retinal ganglion cell axons as they traverse the optic disc. Substantial evidence suggests that the initial site of axonal injury likely occurs at the level of the lamina eribrosa. With the advances of optical coherence tomography （OCT） technologies, such as enhanced depth imaging, swept-source OCT enables us to unveil the lamina eribrosa in vivo features, including lamina cribrosa depth, lamina eribrosa thickness, and the change of lamina cribrosa microarchitecture. The imaging information obtained from these OCT technologies could be used to evaluate the damage of glaucoma, providing effective means for early diagnosis, assessment and prognosis of glaucoma. The studies of lamina cribrosa were reviewed using advanced OCT technologies.
出处
《中华眼外伤职业眼病杂志》
2016年第1期71-77,共7页
Chinese Journal of Ocular Trauma and Occupational Eye Disease
基金
南京医科大学科技发展基金面上项目（2012NJMU259）
无锡市卫生局科研项目计划（Q201309）
关键词
体层摄影术
光学相干
青光眼
筛板
Tomography, optical coherence
Glaucoma
Lamina cribrosa
