摘要
非酒精性脂肪性肝病是最常见的慢性肝脏疾病,它的疾病谱涵盖单纯性肝脏脂肪变、非酒精性脂肪性肝炎,纤维化和肝硬化.目前关于非酒精性脂肪性肝病的病理学诊断仍然是金标准,可以判断肝脏脂肪变程度、炎症分级和纤维化分期,但其有创性及很难动态观察限制了临床使用.新兴的诊断的标志物不断被发现,新的无创性诊断组合也被新近报道,而影像学中核磁共振成像的发展、瞬时弹性超声和受控衰减指数不断发展都为非酒精性脂肪性肝病的非创伤性诊断提供了新方法.
Nonalcoholic fatty liver disease （NAFLD） is the most common chronic liver disease,and the spectrum of this disease includes simple liver steatosis,nonalcoholic steatohepatitis,liver fibrosis,and liver cirrhosis.At present,liver biopsy is still the gold standard for the diagnosis of NAFLD and can determine the degree of steatosis,inflammation grade,and fibrosis stage,but its clinical application is limited by its invasiveness and static nature.New diagnostic markers and noninvasive diagnostic methods have been reportedly recently,and the constant development of magnetic resonance imaging,transient elastography,and controlled attenuation parameter provides new methods for the noninvasive diagnosis of NAFLD.
出处
《中华肝脏病杂志》
CAS
CSCD
北大核心
2016年第2期85-88,共4页
Chinese Journal of Hepatology
关键词
脂肪肝
非酒精性
诊断
病理学
Fatty liver, non-cleoholic
Diagnosis
Pathology
