期刊文献+

我国居民膳食中甜蜜素暴露的理论风险评估 被引量:13

Theoretical risk assessment for dietary exposure to sodium cyclamate in Chinese population
原文传递
导出
摘要 目的评估我国居民膳食中甜蜜素暴露水平及对我国居民健康状况的潜在风险。方法根据GB 2760—2014《食品添加剂使用标准》中规定允许使用甜蜜素的各类食品中甜蜜素的最大使用量和我国居民各类食品实际的消费量数据,采用简单分布模型方法,对我国居民全人群通过各类食品摄入甜蜜素的摄入量进行理论估计,并与国际组织制定的甜蜜素每日允许摄入量(ADI)进行比较。结果我国居民全人群每日通过各类食品摄入甜蜜素的平均水平为0.97 mg/kg BW,占ADI值的13.86%。高暴露人群(P97.5)每日通过各类食品摄入甜蜜素的量为6.69 mg/kg BW,占ADI值的95.52%。根据欧盟食品科学委员会(SCF)制订的ADI(7.00 mg/kg BW),各年龄组人群通过相应食品摄入甜蜜素的平均摄入量均未超过ADI值,但是2-3岁、4-9岁、10-17岁人群中的高暴露人群(P97.5)其甜蜜素的摄入量分别超过甜蜜素ADI的146.32%、86.78%、9.19%;糕点、带壳熟制坚果与籽类对我国居民膳食中甜蜜素暴露的贡献率较高。结论我国居民全人群通过GB 2760—2014中规定允许使用甜蜜素的各类食品摄入甜蜜素的水平均处于安全水平,但是我国部分高暴露人群的暴露水平应引起关注。 Objective In order to assess the potential risk of dietary exposure to sodium cyclamate in Chinese population. Methods The limits of sodium cyclamate in foods and consumption of these foods were used for exposure assessment. The exposure of sodium cyclamate obtained in the present research was compared with the acceptable daily intake( ADI) which was established by JECFA. Results The average exposure of sodium cyclamate exposure of whole Chinese population was 0. 97 mg / kg BW,accounted for 13. 86% of ADI,while high exposure( P97. 5) was 6. 69 mg / kg BW and accounted for 95. 52% of ADI. According to SCF,the intake of sodium cyclamate exposure of high exposures in people under 2-3 years, 4-9 years, 10-17 years( P97. 5) exceeded ADI, was 146. 32%, 86. 78%, 9. 19%,respectively. Pastry,shell cooked nuts and seeds,were the main sources of sodium cyclamate exposure compared with others. Conclusion The sodium cyclamate dietary exposure of whole Chinese population was below the ADI. The sodium cyclamate exposure in high exposures( P97. 5) should be paid more attention to.
出处 《中国食品卫生杂志》 2016年第1期111-114,共4页 Chinese Journal of Food Hygiene
关键词 甜蜜素 膳食暴露 风险评估 中国 理论评估 Sodium cyclamate dietary exposure risk assessment China theoretical appraisal
  • 相关文献

参考文献14

  • 1王虹,王欣欣,曹阳.甜蜜素和蛋白糖对蚕豆根尖细胞的致突变作用[J].江苏农业科学,2014,42(11):61-63. 被引量:4
  • 2中华人民共和国国家卫生和计划生育委员会.GB2760—2014食品安全国家标准食品添加剂使用标准[S].北京:中国标准出版社,2014. 被引量:21
  • 3李宁.国内外甜蜜素限量标准及使用现状分析[J].中国食品卫生杂志,2007,19(5):455-457. 被引量:48
  • 4Serra-Majem L, Ribas L, Ingles C, et al. Cyclamate consumption in Catalonia, Spain (1992) :relationship with the body mass index [J]. Food Addit Contain,1996,13(2) ,695-703. 被引量:1
  • 5IPCS.食品中化学物风险评估原则和方法[M]//刘兆平,李凤琴,贾旭东,译.北京:人民卫生出版社,2012:198-204. 被引量:2
  • 6Price J M,Blava C G,Oser B L,et al. Bladder tumors in rats fed cyclohexylamine or high doses of a mixture of cyclamate and saccharin [ J ]. Science, 1970,167 (3921) : 1131-1132. 被引量:1
  • 7Schmahl D, Habs M. Absence of carcinogenic response to cyclamate and saccharin in Sprague-Dawley rats after transpla- cental application [ J ]. Arzneimittel Forsch, 1980, 30 ( 11 ): 1905-1906. 被引量:1
  • 8Schmahl D, Habs M. Investigations on the carcinogenicity of the artificial sweeteners sodium cyclamate and sodium saccharin in rats in a two-generation experiment [ J ]. Arzneimittel Forsch, 1984,34 ( 5 ) :604-606. 被引量:1
  • 9Mqller-Jenscn O, Knudsen J B, Sqrensen L, et al. Artificial sweeteners and absence of bladder cancer risk in Copenhagen [J]. In J Cancer,1983,32(5) :577-582. 被引量:1
  • 10凌关庭.食品添加剂监管热点和甜蜜素安全性探讨[J].粮食与油脂,2009,22(3):41-44. 被引量:22

二级参考文献41

共引文献95

同被引文献127

引证文献13

二级引证文献70

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部