摘要
目的研究并分析肝硬化并发低钠血症的主要原因与处理策略,以改善患者预后。方法 48例肝硬化并发低钠血症患者,对其临床资料进行回顾性分析。结果 48例患者肝硬化并发低钠血症的主要病因包括摄入不足或排出过多、长期低钠饮食、利尿剂使用不当以及多次放腹水等;重度低钠血症患者的肝性脑病、肝肾综合征发生率明显高于轻度、中度低钠血症患者,差异具有统计学意义(P<0.05);轻度、中度低钠血症患者的血钠纠正率明显高于重度患者,差异具有统计学意义(P<0.05)。结论临床中应掌握肝硬化合并低钠血症的常见病因并根据病因正确处理,积极预防肝性脑病与肝肾综合征等并发症的发生。
Objective To research and analyze pathogenesis and countermeasure for liver cirrhosis complicated with hyponatremia, in order to improve prognosis. Methods A retrospective analysis was made on clinical data of 48 patients of liver cirrhosis complicated with hyponatremia. Results Main pathogenesis of the 48 patients of liver cirrhosis complicated with hyponatremia included insufficiency of intake, redundancy of discharge, long-term low sodium diet, misuse of diuretic, and multiple ascites paracentesis. Patients with severe hyponatremia had obviously higher incidence of hepatic encephalopathy and hepatorenal syndrome than those with mild and moderate hyponatremia. The difference had statistical significance （P〈0.05）. Mild and moderate hyponatremia patients had much higher serum sodium correction rate than severe ones, and the difference had statistical significance （P〈0.05）. Conclusion Comprehension of common pathogenesis of liver cirrhosis complicated with hyponatremia is necessary for making correct treatment and actively preventing complications of hepatic encephalopathy and hepatorenal syndrome.
出处
《中国实用医药》
2016年第2期9-10,共2页
China Practical Medicine
关键词
肝硬化
低钠血症
病因
对策
Liver cirrhosis
Hyponatremia
Pathogenesis
Countermeasure
