摘要
目的探讨阴道镜下病理活检联合宫颈锥切术用于诊断宫颈癌的价值。方法对753例宫颈上皮内瘤变(CIN)的患者行阴道镜活检和宫颈锥切术,术后标本送检,计算阴道镜活检诊断灵敏度、特异度、阳性预测值和阴性预测值。结果753例患者宫颈锥切术确诊CINⅠ级348例,CINⅡ级172例,CINⅢ级160例,浸润癌45例。阴道镜活检的诊断灵敏度94.24%(655/695),特异度为94.24%(34/58),阳性预测值为95.07%(655/689),阴性预测值为37.50%(24/64)。其中CINⅠ级、CINⅡ级、CINⅢ级与宫颈锥切术的符合率分别为95.98%、76.16%、63.13%。结论阴道镜下病理活检对CIN的诊断具有一定价值,但漏诊较多,联合宫颈锥切术可有效提高宫颈癌的早期诊断准确率,避免漏检。
Objective To explore the value of colposcopic biopsy combined with cervical conization in diagnosis of cervical cancer. Methods Totally 753 patients with cervical intraepithelial neoplasias（ CIN） were treated with colposcopic biopsy and cervical conization. After operation,specimens were inspected and the sensitivity,specificity,positive predictive value and negative predictive value of colposcopic biopsy were calculated. Results There were 348 cases of grade Ⅰ,172 cases of grade Ⅱ and 160 cases of grade Ⅲ in CIN. The sensitivity,specificity,positive predictive value and negative predictive value of colposcopic biopsy were 94. 24%（ 655 /695）,94. 24%（ 34 /58）,95. 07%（ 655 /689） and 37. 50%（ 24 /64）. The coincidence rate between grade Ⅰ,grade Ⅱ,gradeⅢ and cervical conization were 95. 98%,76. 16% and 63. 13%. Conclusion Colposcopic biopsy is valuable in the diagnosis of CIN,but the missed diagnoses are too much. Colposcopic biopsy combined with cervical conization can improve early diagnosis accuracy and avoid missed diagnosis.
出处
《实用临床医药杂志》
CAS
2016年第3期72-74,共3页
Journal of Clinical Medicine in Practice
基金
中国高校医学期刊临床专项资金(11523686)
关键词
宫颈癌
阴道镜
宫颈锥切术
cervical cancer
colposcope
cervical conization
