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光学相干断层成像对支架内再狭窄冠脉内膜病理特点的观察 被引量:15

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摘要 目的:探索冠心病支架内再狭窄患者靶病变组织特点,为理解支架内再狭窄病理改变以及处理支架内再狭窄提供临床证据。方法:入选冠脉造影显示支架内再狭窄患者,其中置入支架1年左右进行光学相干断层成像(OCT)检查者纳入本研究,分析支架内再狭窄部位组织病变特点:同时分析支架内新生内膜增殖情况。结果:12例患者中OCT扫描13枚支架。其中1例患者序贯置入2枚支架,共考察支架小梁3 930个,内膜覆盖率为88.27%,其余11.72%为内皮化不全;内皮化不全的支架小梁中,支架贴壁不良率3.25%,存在支架外钙化者2.17%。考查OCT截面331帧,其中新生内膜厚度10-99μm者的比率为22.36%,100-199μm之间者为25.08%,200μm及以上者52.57%。5例再狭窄主要病理改变为纤维组织增生,7例为新生动脉粥样斑块。结论:冠脉支架置入1年的支架内再狭窄患者其支架处内皮化不全与过度增殖并存,其病理改变为新生动脉粥样斑块与纤维组织增生,而且两者所占比例相当。
出处 《实用医学杂志》 CAS 北大核心 2016年第1期94-97,共4页 The Journal of Practical Medicine
基金 国家自然科学基金(编号:81473507) 郑州市科技创新团队基金(编号:121PCXTD520)
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参考文献16

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二级参考文献37

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