摘要
[目的]观察辨证分型联合西药治疗慢性阻塞性肺疾病急性加重呼吸衰竭疗效。[方法]使用随机平行对照方法,将104例住院患者按掷骰子法简单随机分为两组。对照组52例青霉素钠,80IU/次,3次/d,肌注;左氧氟沙星,200m L/次,2次/d,静滴;甲硝唑,0.6~1.2g/次,3次/d;氯化铵,10m L/次,3~4次/d。治疗组52例痰湿壅肺-祛痰燥湿汤（姜半夏15g,茯苓、陈皮各10g,苏子、厚朴、橘红各8g）;痰热壅肺-清肺化痰汤（黄芩12g,瓜萎15g,法半夏、川贝母各10g,桔梗、麦冬各8g）;外寒内饮-小青龙汤（麻黄、桂枝各9g,干姜6g,白芍9g,细辛3g,法半夏9g,五味子6g,紫苏子、杏仁、厚朴各9g,甘草炙6g）;风寒袭肺-三拗汤（麻黄、杏仁、荆芥、紫苏叶、白前各9g,百部12g,桔梗、枳壳、陈皮、甘草炙各9g）;痰蒙神窍-涤痰汤（半夏9g,天南星、天竺黄各6g,茯苓15g,陈皮、枳实各9g,丹参15g,人参9g,石菖蒲6g,细辛3g,生姜6g）,1剂/d,水煎400m L,早晚口服,200m L/次;西药治疗同对照组。连续治疗14d为1疗程。观测临床症状、死亡率、不良反应。连续治疗2疗程,判定疗效。[结果]治疗组显效40例,有效11例,无效1例,总有效率98.08%。对照组显效35例,有效7例,无效10例,总有效率80.77%。治疗组疗效优于对照组（P〈0.01）。死亡率治疗组低于对照组（P〈0.05）。[结论]辨证分型联合西药治疗慢性阻塞性肺疾病急性加重呼吸衰竭疗效满意,无严重不良反应,值得推广。
[Objective]To observe Syndromes Combined with Western treatment of chronic obstructive pulmonary disease exacerbations respiratory failure.[Methods]Randomized parallel controlled method,104 cases of hospitalized patients were randomly divided into two groups craps method is simple.52 cases in the control group sodium penicillin,80IU/time,3 times/d,intramuscular injection;levofloxacin,200 m L/times,2 times/d,intravenous infusion;metronidazole,0.6~1.2g/time,3 times/d;chlorine ammonium,10 m L/time,3 to 4 times/d.Treated 52 cases of phlegm obstruct the lung-expectorant dampness soup（Jiangbanxia 15 g,Fuling,Chenpi 10 g,Suzi,Houpu,Juhong each 8g）;phlegm obstruct the lung-clearing the lungs phlegm soup（Huangqin 12 g,Gualou 15 g,Fabanxia,Chuanbeimu each 10 g,Jiegeng,Maidong each 8g）;the outer cold drink-XQLD（Mahuang,Guizhi 9g,Ganjiang 6g,Baishao 9g,Xixin 3g,Fabanxia 9g,Wuweizi 6g,Zisuzi,Xingren,Houpu each 9g,Gancao 6g）;cold passage of the lung-three bend soup（Mahuang,Xingren,Jingjie,Zisuye,Baiqian each 9g,Baibu 12 g,Jiegeng,Zhike,Chenpi,Gancao each 9g）;sputum awakened by God-Ditan soup（Banxia 9g,Tiannaxing,Tianzhuhuang each 6g,Fuling 15 g,Chenpi,Zhishi each 9g,Danshen 15 g,Renshen 9g,Shichangpu 6g,Xixin 3g,Shengjiang 6g）,1 ji/d,decoction 400 m L,sooner or later,oral,200 m L/times.Western medicine with the control group.14 d for a course of continuous treatment.Observation of clinical symptoms,mortality,adverse reactions.2 courses of continuous treatment,to determine efficacy.[Results]The treatment group 40 cases,effective in 11 cases,one case,the total efficiency of 98.08%.The control group 35 cases markedly effective in 7 cases,10 cases,the total efficiency of 80.77%.Treatment group than the control group（P0.01）.Mortality treatment group than the control group（P0.05）.[Conclusion]Syndromes combined with western treatment of chronic obstructive pulmonary disease with acute exacerbation of respiratory failure results were satisfactory,no serious adverse reactions,it is worth promoting.
出处
《实用中医内科杂志》
2015年第12期146-148,共3页
Journal of Practical Traditional Chinese Internal Medicine
关键词
慢性阻塞性肺疾病急性加重呼吸衰竭
肺胀
辨证分型
青霉素钠
左氧氟沙星
甲硝唑
氯化铵
死亡率
中西医结合治疗
随机平行对照研究
chronic obstructive pulmonary disease with acute exacerbation of respiratory failure
lung inflation
syndromes
sodium penicillin
levofloxacin
metronidazole
ammonium chloride
mortality
integrative medicine
randomized controlled study
