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清热化痰汤治疗痰热郁肺型小儿肺炎支原体感染支气管炎随机平行对照研究 被引量:5

Qingre Huatantang Treated Tanre Yufei Pulmonary Mycoplasma Pneumoniae Infection Bronchitis Randomized Controlled Study
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摘要 [目的]观察清热化痰汤治疗痰热郁肺型小儿肺炎支原体感染支气管炎疗效。[方法]使用随机平行对照方法,将86例门诊患者按抛硬币法简单随机分为两组。对照组43例阿奇霉素,第1d剂量为10mg·kg^(-1),第2~7d剂量为5mg·kg-1,1次/d,饭前1h口服。治疗组43例清热化痰汤(麻黄蜜炙3g,苦杏仁6g,生石膏先煎10g,瓜蒌仁、百部蜜炙各6g,川黄芩3g,川贝研末冲服1.5g,桔梗、板蓝根各6g,甘草3g;体温较高加鱼腥草、金银花;咳嗽痰多加青黛、紫苑;食欲不振加陈皮、山楂;大便秘结加大黄、火麻仁;喘息甚加白果、葶苈子),1剂/d,武火煮沸后文火熬制,水煎400m L,早晚餐后30min口服,200m L/次。连续治疗7d为1疗程。观测临床症状、哮鸣音、ELISA、不良反应。治疗1疗程,判定疗效。[结果]治疗组痊愈10例,显效15例,有效18例,无效0例,总有效率100.00%。对照组痊愈8例,显效14例,有效16例,无效5例,总有效率88.37%。治疗组疗效优于对照组(P<0.05)。症状消失时间治疗组改善优于对照组(P<0.05)。[结论]清热化痰汤治疗痰热郁肺型小儿肺炎支原体感染支气管炎疗效满意,无严重不良反应,值得推广。 [Objective]To observe the phlegm phlegm Yu Treated Mycoplasma pneumoniae infection in children with pulmonary bronchitis.[Methods]Randomized parallel controlled method,86 outpatients by disease Zhi No.lottery method is simple and randomly divided into two groups.The control group of 43 patients with azithromycin,the first 1d dose of 10mg·kg-1,the first 2~7d dose of 5mg·kg-1,1 times/d,orally 1h before meals.The treatment group 43 cases Qingre Huatan Tang(Mahuang 3g,Kuxingren 6g,Shengshigao 10 g,Gualouren,Baibu each 6g,Chuanhuangqin 3g,Chuanbei 1.5g,Jiegeng,Banlangen each 6g,Gancao 3g;high temperature plus Yuxin gcao,Jinyinhua;cough,phlegm plus Qingdai,Ziyuan;loss of appetite add Chenpi,Shanzha;constipation increased Dahuang,Huomaren;respite even add Baiguo,Tinglizi),1 agent/d,heat to boil simmer after boil,cook 400 m L,morning and evening meal 30 min oral,200 m L/times.Western medicine with the control group.7d for a course of continuous treatment.Observation of clinical symptoms,cough,wheeze,adverse reactions.One course of treatment,to determine efficacy.[Results]The cure 10 cases,15 cases markedly effective in 18 cases,ineffective 0 cases,the total efficiency of 100.00%.The control group recovered eight cases,14 cases markedly effective in 16 cases,5 cases,the total efficiency of 88.37%.Treatment group than the control group(P0.05).Time treatment group improved symptoms than the control group(P0.05).[Conclusion]Qingre Huatan Tang Treated pulmonary bronchitis in children with Mycoplasma pneumoniae infection results were satisfactory,no serious adverse reactions,it is worth promoting.
作者 李杏儿
出处 《实用中医内科杂志》 2015年第12期44-46,共3页 Journal of Practical Traditional Chinese Internal Medicine
关键词 小儿肺炎支原体感染支气管炎 咳嗽 痰热郁肺 清热化痰汤 阿奇霉素 哮鸣音 ELISA 中医药治疗 随机平行对照研究 mycoplasma pneumoniae infection bronchitis cough phlegm Yu Lung Qingre Huatan Tang azit hromycin wheezing ELISA medical treatment randomized controlled study
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