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胃癌前病变的内镜治疗进展 被引量:5

Endoscopic Management Progress of Precancerous Conditions and Lesions in the Stomach
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摘要 胃癌是全球范围内病死率较高的恶性肿瘤之一,究其原因在于对胃癌前疾病癌变的预警、预防不够,需要重视胃癌前病变诊断、治疗。随着内镜技术不断发展,胃癌前病变可采用内镜下手术治疗,相比于外科手术,其创伤小、疗效好、花费低,其中内镜黏膜下剥离术(ESD)为一种基于内镜下黏膜切除术(EMR)发展起来的技术,其病变整块切除率及完全切除率高于EMR。但ESD术所需手术时间长,需要有经验的内镜医师进行手术,术中存在较高的穿孔、出血风险性。 Gastric cancer remains one of the most common causes of cancer related with mortality worldwide. This means that there is a need for early detection and diagnosis of premalignant gastric lesions in clinical practice. In recent years, there has been tremendous progress in endoscopic techniques. Endoscopic resection (ER) is at present an accepted treatment for premalignant gastric lesions. ER provides similar efficacy to surgery~ however, it is minimally invasive and less expensive. Endoscopic submucosal dissection (ESD) is a new method of endoscopic resection that can achieve higher rate of en bloc resection and complete resection rate than endoscopic mucosal resection (EMR) for treatment of premalignant gastric lesions. However, compared to EMR, ESD requires a longer procedure time and a higher level of technical expertise, in addition to having a slightly greater risk of complications. Perforation and bleeding are the major complications associated with gastric ESD.
作者 张澍田 程芮
出处 《医学与哲学(B)》 2015年第12期15-17,34,共4页 Medicine & Philosophy(B)
关键词 胃癌前病变 内镜治疗 内镜黏膜下剥离术 内镜下黏膜切除术 gastric precancerous lesion, endoscopic management, endoscopic mucosal resection (EMR), endoscopicsubmucosal dissection (ESD)
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