摘要
目的探讨针药结合治疗冠心病复杂性室性早搏的作用机制,为临床治疗冠心病复杂性室性早搏提供一种疗效显著、操作安全简便、无不良反应的新途径。方法将99例冠心病复杂性室性早搏患者随机分为稳心颗粒加针刺治疗组、稳心颗粒对照组和针刺对照组。入选患者均停用其他抗心律失常药物,但不停用治疗原发基础疾病的药物,三组患者均治疗1个月,观察三组患者临床症状、心电图、动态心电图及肝肾功能,并进行统计学分析。结果针药组患者治疗效果明显优于稳心组、针刺组,总有效率达90.9%,稳心组患者治疗效果优于针刺组,有效率为63.6%。针药组治疗前后疗效比较差异有统计学意义(P<0.01);稳心组治疗前后疗效比较差异有统计学意义(P<0.01);针刺组治疗比较差异未见统计学意义(P>0.05)。治疗后,24 h动态心电图室性早搏减少数针药组大于稳心组(P<0.05)及针刺组(P<0.01),且稳心组治疗后24 h动态心电图室性早搏减少数大于针刺组(P<0.01)。结论针药结合治疗冠心病复杂性室性早搏的效果优于单用药物治疗或针刺治疗,单用药物治疗的结果优于单用针刺治疗。
Objective To investigate the effect of acupuncture and medicine combined treatment on coronary heart disease （CHD）complicated with complex ventricular premature beat,and thus provide a new way of significant effect,safe,convenient operation and no adverse reactions for the clinical treatment of coronary heart disease complicated with ventricular premature beat. Methods Ninety-nine coronary heart disease patients complicated with complex ventricular premature beat were divided into Wenxin granule plus acupuncture treatment group,Wenxin granule group and acupuncture group. Patients were all deactivated other antiarrhythmic drugs,but still accepted treatment for primary disease drugs. The three groups were treated for 1 month,the clinical symptoms,electrocardiogram and dynamic electrocardiogram,liver and kidney function were observed. Results The treatment effect of Wenxin granule plus acupuncture treatment group was significantly better than that of Wenxin granule group and acupuncture group,the total effective rate was 90. 9% ;the effect of Wenxin granule group was better than that of acupuncture group,and the effective rate was 63. 6% . Before and after treatment,the effect had significant difference in the Wenxin granule plus acupuncture treatment group and Wenxin granule group（P 0. 05）. After treatment,the 24 h dynamic electrocardiogram of ventricular premature beat reduce number of Wenxin granule plus acupuncture treatment group was better than that of Wenxin granule group（P 〈 0. 05）and acupuncture group （P 〈0. 01）. After treatment,24 h dynamic electrocardiogram of ventricular premature beat reduce number of Wenxin granule group was better than that of acupuncture group（P 〈 0. 01）. Conclusion Combination of acupuncture and medicine in the treatment of coronary heart disease（CHD）complicated with complex ventricular premature beat is better than the results of single drug therapy or acupuncture therapy;the effect of single drug treatment is better than that of single acupuncture tre
出处
《临床医学》
CAS
2015年第12期1-3,共3页
Clinical Medicine
基金
广西壮族自治区中医药管理局自筹项目(922C1150)
南宁市科技局自筹项目(ZC2011003C)
南宁市青秀区科技局基金项目(2011S06)
关键词
针药结合
冠心病复杂性室性早搏
稳心颗粒
针刺
Acupuncture combined with medicine
Coronary heart disease complicated with complex ventricular premature beat
Wenxin granule
Acupuncture
