摘要
目的:了解肇庆市第二人民医院(以下简称"我院")药品不良反应(adverse drug reaction,ADR)报告中的不合理用药情况,促进临床合理用药。方法:收集我院2010—2014年470例ADR报告,对其不合理用药情况进行审核与分析。结果与结论:470例ADR报告中,共有79例不合理用药情况,以儿童及老年患者居多。涉及药物包括抗菌药物、中药及中成药制剂、神经系统用药、调节电解质及酸碱平衡药、心血管系统用药、呼吸系统用药等6大类,其中以抗菌药物为主,其次是中药及中成药制剂。不合理用药以超剂量用药、配伍不当、无适应证用药等较为突出。应引起医药人员的高度重视,加强临床合理用药培训和指导,促进合理用药,避免不必要的ADR发生。
OBJECTIVE：To investigate the irrational drug use in the adverse drug reactions（ ADR） reports from the Second People＇s Hospital of Zhaoqing（ hereinafter referred to as ＂our hospital＂）,and to promote the rational drug use in clinic.METHODS：470 cases of ADR reports in our hospital during 2010-2014 were collected,of which the irrational drug use would be reviewed and analyzed.RESULTS CONCLUSIONS：Of the 470 cases,there were 79 cases of irrational drug use,the majority were children and elderly people.The involved drugs mainly included 6types：antibiotics,TCM and Chinese patent medicine preparation,drugs of nervous system,drugs that regulate the electrolyte and acid-base imbalance,drugs for cardiovascular diseases and drugs for respiratory system;among which the majority were antibiotics,followed by Chinese patent medicine preparation.The mainly irrational drug use situations were overdose drug use,improper compatibility and no indications for drug use,etc;the medical workers should pay high attention to these phenomenon.It is necessary to strengthen the train and guidance of rational drug usefor clinician and pharmacists,so as to promote the ration drug use and avoid the occurrence of unnecessary ADR.
出处
《中国医院用药评价与分析》
2015年第11期1505-1507,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
药品不良反应
不合理用药
再评价
审核
Adverse drug reactions
Irrational drug use
Revaluation
Review
