摘要
目的分析早、晚期透析对终末期肾病患者生存率及心血管事件发生率的影响。方法选取本院2010年5月—2013年5月收治的80例终末期肾病患者作为研究对象,按随机数字表法分为A、B两组各40例。A组接受早期透析治疗,B组则给予延迟透析治疗,两组均随访2年,比较其生存率及心血管事件发生率。计数资料采用χ2检验,P<0.05为差异有统计学意义。结果 A组随访1年、18月、2年生存率分别为100.0%、97.5%、90.0%,与B组随访生存率比较,差异均无统计学意义(均P>0.05);A组住院率为35.0%,心血管事件发生率为15.0%,腹膜炎发生率为20.0%,血管通路并发症发生率为20.0%,上述指标与B组比较,差异均无统计学意义(均P>0.05)。结论早、晚期透析治疗对终末期肾病患者生存率及心血管事件发生率的影响无明显差异,目前最佳透析时间依然较难下定论,透析时机的选择应从患者整体情况作综合分析,而不能仅依靠部分肾功能指标。
Objective To analyze the effect of early and late stage dialysis on survival rate and occurrence of cardiovascular events in patients with end stage renal disease. Methods 80 patients with end- stage renal disease treated in our hospital from May 2010 to May 2013 were selected as the research objects. According to the random number table method,the patients were divided into group A and B with 40 cases in each group. Group A was treated with early stage dialysis while group B was treated with delayed dialysis. The two groups were followed up for 2 years. The survival rates and the incidence rates of cardiovascular events were compared. Count data was wsde by chi square test,P〈0. 05 was considered statistically significant. Results With one year,18 months and 2 years of follow- up,the survival rates of group A were100. 0%,97. 5% and 90. 0%,respectively. Compared with those of group B,the differences were not statistically significant（ all P〉0. 05）. The hospitalization rate of group A was 35. 0%,the incidence of cardiovascular events was 15. 0%,the incidence of peritonitis was 20. 0%,and the incidence of vascular access complications was 20. 0%. Compared the above indexes with those in group B,the differences were not statistically significant（ all P〉0. 05）. Conclusions The effect of early and late stage dialysis on the survival rate and the incidence of cardiovascular events in patients with end-stage renal disease has no obvious difference. At present,the best time of dialysis is still difficult to be determined. The selection of dialysis opportunity should be comprehensively analyzed according to the general condition of patients rather than depending on part of the renal function indexes.
出处
《社区医学杂志》
2015年第24期22-24,共3页
Journal Of Community Medicine
关键词
透析
终末期肾病
心血管事件
生存率
Dialysis
End stage renal disease
Cardiovascular events
Survival rate
