摘要
目的:探讨在药品标准中采用拉曼光谱方法作为注射液鉴别项的科学性、可行性和有效性。方法:采用拉曼光谱法,以相应对照品的水溶液的拉曼光谱作为参考光谱,对《中国药典》2010年版二部中采用红外光谱法鉴别的8个注射液品种进行定性鉴别。结果:拉曼光谱法能够对氨茶碱注射液等8个品种进行鉴别。结论:拉曼光谱法用于注射液品种的定性鉴别,具有不需要复杂的样品前处理,可直接测定,准确度高,不受水分干扰等优点,可作为药品标准中一些注射液及其他溶液制剂定性鉴别的方法之一。
Objective： To find out whether the Raman spectroscopy was scientific and effective as an identification method of injectionsin drug standard. Method： Raman spectra of reference substances were used as reference spectra, 8 injection varieties recorded in Chinese Pharmacopeia 2010 Edition Vol. 11 that using IR method were identified. Results： Raman spectroscopy could identify Aminophylline Injection and other 8 varieties. Conclusion： Raman spectroscopy used to the qualitative identification of a variety of injections has some advantages, such as no need complex sample pre-processing, direct determination, high-accuracy and not affected by moisture, etc. It can be one of methods for the qualitative identification of some injections and other solutions in the pharmaceutical standard.
出处
《中国药品标准》
CAS
2015年第6期416-420,共5页
Drug Standards of China
关键词
注射液
拉曼光谱法
鉴别
药典方法
injections
Raman spectroscopy
identification
pharmacopeia methods
