摘要
目的研究酸性氧化电位水对危重患者置管感染的预防作用,为临床置管感染的预防提供依据。方法选择2013年1月-2015年6月住院患者1 708例,按随机数表法将其分为研究组和对照组,每组各854例,对照组患者使用生理盐水和聚维酮碘对经口气管置管、留置导尿管及中心静脉置管进行消毒,每天消毒3次,对于出现感染的患者适当增加干预次数;研究组使用酸性氧化电位水对经口气管置管、留置导尿管及中心静脉置管进行消毒,每天消毒2次;观察并记录干预后两组患者的感染率及消毒前后平均菌落数目,结果数据采用SPSSl6.0软件进行统计分析。结果患者总感染率研究组为6.0%、对照组患者为28.1%,两组比较差异有统计学意义(P<0.05);两组患者干预前平均菌落数相比较差异无统计学意义,消毒后研究组患者平均菌落数为16CFU/cm2、杀灭率为80.0%;干预10min后平均菌落数为2CFU/cm2、杀灭率为97.5%,与对照组相比较,干预后研究组平均菌落数明显较少,差异有统计学意义(P<0.05)。结论对于危重患者置管感染的预防与控制中,使用酸性氧化电位水的消毒作用明显。
OBJECTIVE To study the prevention effect of acidic electrolyzed oxidizing water on critical patients with hospital infections,so as to provide basis for clinical prevention of catheter infections.METHODS A total of 1708 cases of hospitalized patients between Jan.2013 and Jun.2015 were chosen and divided into the observation group and the control group by random table method,854 cases in each group.For the control group,the breath tube,indwelling urethral catheter and central venous indwelling catheter were sterilized using physiological saline and povidone iodine,3times a day,and the number of interventions was increased for infected patients.For the observation group,the breath tube,indwelling urethral catheter and central venous indwelling catheter were sterilized using acidic electrolyzed oxidizing water,2times a day.The infection situation of two groups of patients after intervention and the average number of bacterial colonies before and after sterilization were observed and recorded.Data were statistically analyzed by software SPSSl6.0.RESULTS The overall infection rate was 6.0%and the total infection rate in the control group was 28.1%,the differente was significant（P〈0.05）.There was no significant difference in the average count of bacteria between the two groups of patients before intervention.The average count of bacteria and the killing rate were 16CFU/cm2 and 80.0% after sterilization and 2CFU/cm2 and 97.5%at 10 min after intervention in the observation group.The average count of bacteria was significantly decreased in the observation group compared to the control group after intervention（P〈0.05）.CONCLUSIONFor prevention and control of hospital infections due to catheter in critical patients,using acidic electrolyzed oxidizing water for sterilization has obvious effect.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2016年第4期942-943,946,共3页
Chinese Journal of Nosocomiology
基金
山东省自然科学基金资助项目(Y2006C02)
关键词
危重患者
酸性氧化电位水
置管感染
预防效果
Critically ill patients
Acidic electrolyzed oxidizing water
Catheter infection
Protective effect
