摘要
目的:对应用血清β_2-微球蛋白与免疫球蛋白联合检测方式对患有多发性骨髓瘤疾病的患者的病情实施诊断的临床价值进行研究。方法:选择在某院就诊的患有多发性骨髓瘤疾病的患者和同期接受健康体检的健康人资料各52例,分别定义为研究组和对照组。采用免疫比浊法对两组β_2-微球蛋白和IgM水平进行测定;采用溴甲酚绿法对两组IgA和IgG水平进行测定,比较测定结果。结果:研究组研究对象的β_2-微球蛋白、IgA、IgG水平明显高于对照组,组间差异显著(P<0.05);研究组研究对象IgM水平明显低于对照组,组间差异显著(P<0.05)。结论:患有多发性骨髓瘤疾病的患者的血清β_2-微球蛋白与免疫球蛋白两项指标水平会出现明显异常,可作为临床疾病诊断的重要参考。
Objective:To study the clinical value of the application of the combined detection of serum β2-microglobulin and immunoglobulin to determine the situation of patients with multiple myeloma.Methods:Select the data of 52 patients with multiple myeloma and another 52 cases of concurrent healthy people received physical examination in some hospital and defined them as research group and control group respectively.Detect the level of β_2-microglobulin and IgM of the 2 groups in accordance with turbidimetric inhibition immunoassay;and determine the level of IgA and IgG of the 2 group with bromocresol green.Compare the results.Results:The level of β_2-microglobulin,IgA and IgG of the objects in the research group levels were significantly higher than those in the control group,the differences between groups were significant(P<0.05);the level of IgM of the objects in research group was significantly lower than that in control group,the difference between groups was significant(P<0.05).Conclusion:There would be obvious abnormality in β_2-microglobulin and immunoglobulin of the patients with multiple myeloma,it can be used as an important reference for clinical diagnosis of diseases.
出处
《数理医药学杂志》
2016年第2期213-214,共2页
Journal of Mathematical Medicine
