摘要
以三聚氯氰（CYC）、二乙醇胺（DEA）和伯胺为反应剂,分步考察碱催化剂、反应时间等对胺亲核取代嗪氯反应结果的影响,并在此基础上合成了一系列的多元羟烷胺基-1,3,5-三嗪（3a,3b,3c）,其结构均经元素分析、FTIR、1H NMR和ESI-MS表征。结果表明,CYC第一、二、三氯的取代反应,宜分别选二乙醇胺、三乙胺和碳酸氢钠作碱催化剂,并依次在-1-5℃、45-50℃和85-90℃下反应2 h、7 h和16 h;所得多元羟烷胺基-1,3,5-三嗪具有双亲性.
The effects of base catalyst, reaction time and other reaction conditions on the nucleophilic substitution reaction of ammonolysis of triazine chloride were investigated according to the reaction steps by employing cyanuric chloride （CYC） , diethanolamine （DEA） and primary amine as reactants. On the basis of this, a series of muhi-hydroxyalkyl amine-1, 3, 5-triazines （3a, 3b, 3c） were synthesized from the reactants and characterized by element analysis, FTIR, ^1H NMR and ESI-MS. It was found that the optimal reaction conditions for aminolysis - substitution of the first to third chlorine of CYC were as follows ： respectively using DEA, triethylamine （TEA） and sodium bicarbonate as base catalyst, and successively reacting at - 1 - 5 ℃ for 2 h, 45 - 50 ℃ for 7 h and 85 - 90 ℃ for 16 h. And the resulting multi-hydroxyalkyl amine-1, 3, 5-triazines were proved to be amphiphilic.
出处
《福建师范大学学报（自然科学版）》
CAS
CSCD
北大核心
2016年第1期31-38,共8页
Journal of Fujian Normal University：Natural Science Edition
基金
福建省教育厅科技计划项目(JA12236)
福建省自然科学基金资助项目(2011J01287)
关键词
双亲
羟烷胺基-1
3
5-三嗪
亲核取代
合成
amphiphilic
hydroxyalkyl amine-1, 3, 5-triazine
nucleophilic substitution
synthesis
