摘要
目的观察宫颈癌患者调强放疗联合顺铂治疗疗效及不良反应。方法选取2008年6月~2015年9月收治的50例宫颈癌患者,随机分成对照组和观察组各25例,对照组实施调强放疗（IMRT）,观察组在对照组基础上增加同步顺铂化疗。观察对比两组疗效及不良反应。结果两组患者近期疗效、1年生存率及其他评判指标差异无统计学意义（P〉0.05）;观察组3、5年生存率及其他评判指标均优于对照组优（P〈0.05）;两组患者不良反应主要表现在放射性直肠炎及白细胞反应率两方面,对比得出,观察组优于对照组（P〈0.05）。结论调强放疗联合顺铂治疗宫颈癌疗效比单纯调强放疗优良。
Objective To observe the therapeutic effect and adverse reactions of radiotherapy combined with cisplatin in patients with cervical cancer. Methods 50 cases of cervical cancer patients treated in June 2008 to September 2015 were randomly divided into control group and observation group,25 cases in control group were treated with intensity modulated radiotherapy（IMRT）. Observation and comparison of the efficacy and adverse reactions of the two groups. Results Two groups of patients with clinical efficacy,the 1 year survival rate and other indexes showed no significant difference（P〉0.05）. The observation group of 3,5 year survival rate and other evaluation indicators were excellent compared with the control group（P〈0.05）. Two groups of patients with adverse reactions mainly in radiation proctitis and leukocyte response rate,after the comparison,found that the observation group was better than the control group（P〈0.05）. Conclusion The therapeutic effect of combination therapy with cisplatin in the treatment of cervical cancer is better than that of simple intensity modulated radiotherapy.
出处
《中国卫生标准管理》
2015年第32期108-109,共2页
China Health Standard Management
关键词
宫颈癌
调强放疗
顺铂化疗
疗效
不良反应
Cervical cancer
Intensity modulated radiotherapy
Cisplatin chemotherapy
Curative effect
Adverse reaction
