摘要
目的：探讨及比较神经内镜手术与传统显微手术治疗垂体腺瘤的临床价值。方法：选取2012年4月～2015年2月于天门市第一人民医院进行手术治疗的58例垂体腺瘤患者为研究对象，将其随机分为对照组（传统显微手术组）29例和观察组（神经内镜手术组）29例，然后将两组患者的术前及术后不同时间的血清应激、激素指标及增殖相关指标进行比较。结果：治疗前两组患者的血清应激、激素指标及增殖相关指标比较，差异均无统计学意义（P〉0．05）；而治疗后不同时间观察组的血清应激指标均低于对照组，两组治疗后的血清激素及增殖相关指标均低于治疗前，差异具有统计学意义（P〈0．05）；但两组治疗后的血清激素及增殖相关指标比较，差异均无统计学意义（P〉0．05）。结论：神经内镜手术治疗垂体腺瘤的临床价值相对高于传统显微手术，其在保证病灶治疗效果的基础上对机体造成的不良应激相对更小。
Objective： To investigate and compare the clinical effects of neuroendoscopic surgery and traditional micro- surgery for pituitary adenoma. Methods：A total of 58 patients with pituitary adenoma who underwent surgery in our hospital from April 2012 to February 2015 were selected and randomly divided into traditional microsurgery group and neuroendoscopic surgery group with 33 cases in each group. Then the serum stress, hormones and proliferation related indexes of two groups be- fore the surgery and at different time after the surgery were compared. Results：Before undergoing surgery, serum stress, hor- mones and proliferation related indexes of two groups were not significant different （P〈0. 05） ,while the serum stress indexes of neuroendoscopic surgery group at different time after the surgery were all lower than those of traditional microsurgery group. After treatment, the serum hormones and proliferation related indexes of two groups were all lower than those before the treatment （P all〈 0.05）. However, there was no significant difference in serum hormones and proliferation related inde-xes between the two groups （P all〉0.05）. Conclusion： Neuroendoscopic surgery shows better effects for pituitary adenomand than traditional microsurgery with advantages of less stress responsive reactions and better treatment effects.
出处
《海南医学院学报》
CAS
2016年第5期457-459,共3页
Journal of Hainan Medical University
基金
贵州省科技基金项目[黔科合J2013(2311)]~~
关键词
垂体腺瘤
神经内镜手术
传统显微手术
应激指标
激素指标
增殖相关指标
Neuroendoscopic surgery
Traditional microsurgery
Responsive reaction related indexes
Hormones
Pro- liferation related indexesPituitary adenoma
clinical value
