摘要
目的:观察养心开郁片抗疲劳、抗炎作用。方法:采用小鼠负重游泳时间测定方法,研究养心开郁片的抗疲劳作用;采用慢性应激抑郁模型(CUS)大鼠血清IL-6、TNF-a含量测定方法,研究养心开郁片的抗炎作用。结果:养心开郁片大剂量组较空白对照组小鼠游泳时间延长(P<0.05);较模型对照组大鼠血清IL-6、TNF-a含量降低(P<0.05);与路优泰对照组作用相当。结论:养心开郁片具有明显抗疲劳、抗炎作用。
Objective： To observe the anti-fatigue and anti-inflammation effects of Yangxinkaiyu tablets. Methods： The loaded swimming time of mice is determined to research the anti-fatigue effect of Yangxinkaiyu tablets; determination of IL-6 and TNF-α in serum through the depression rat model of chronic stress （CUS） is used to study the anti-inflammation effect of Yangxinkaiyu tablets. Results： Compared with the blank control group, the large dosage Yangxinkaiyu tablets group prolonged the swimming time of mice （ P 〈 0. 05 ）. Compared with the model control group, the levels of IL-6 ,TNF-α in serum was lower （P 〈0. 05 ） , having the similar functions with neurostan control group. Conclusion： Yangxinkaiyu tablets have obvious anti-fatigue and antiinflammation effects.
出处
《贵阳中医学院学报》
2016年第1期26-28,共3页
Journal of Guiyang University of Chinese Medicine
基金
陕西省科技统筹创新工程计划项目
项目编号:2011KTCQ03-01
关键词
养心开郁片
抑郁症
抗疲劳
抗炎
Yangxinkaiyu tablets
depression
anti-fatigue
anti-inflammation
